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Hematologia > Linfoma Primário de Mediastino > Flashcards

Linfoma Primário de Mediastino Flashcards

1
Q

Via molecular o LPMediastino

A

NFKb - 9p24.1
JAK-STAT - 2p16

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2
Q

Clínica - PMBCL

A

Massa mediastinal anterior
trombose
sd. compressivas
SVC

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3
Q

microscopia - PMBCL

A

aglomerado difuso entremeado por locais de esclerose.

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4
Q

IGP - PMBCL

A

Positivo: CD45, CD20, CD19, CD22, CD79a, CD30 (80% fraco e heterogêneo). CD200, CD23, MAL (100% de especificidade), TRAF1 e cREL (diferente do difuso). PDL1
Perda: sIg
Negativo: CD10, CD21, CD15

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Hematologia (13 decks)

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