LIMBIC SYSTEM CLINICAL Flashcards
The term ______ refers to the encoding, storage, and retrieval of information. A defect in one or more of these processes results in amnesia
memory
_________refers to conscious retrieval of information. It supports the learning and retention of facts and the conscious recollection of prior events (knowing that).
Explicit memory
Types of explicit memory
(1) episodic: personally experienced facts and events with special spatial and temporal localization
(2) semantic: memory of culturally and educationally acquired encyclopedic knowledge such as the meaning of words, arithmetical facts, and geographic and historical information
Duration of long vs short term memory
1 minute
________supports the learning and retention of skills (knowing how).
Implicit memory
Types of Implicit memory
(1) procedural memory : It is characteristically resistant to forgetting, hence its preservation in patients who are otherwise amnesic.
and (2) priming: short-lived enhancement of perceptually based performance following recent exposure to visually similar material
Immediate memory may be explained as a __________ at the synapse; longer-lasting memory may be explained as an ___________ of the synapse
transient electric alteration
actual physical or chemical alteration
Anatomic correlates
1. Episodic Memory______
(no new information is ever retained beyond the span of 40β60 seconds.)
2. Semantic_________
- Short-Term (Working) Memory
- Procedural (Skill Learning) Memory
- Priming
- Mesial temporal cortex
- Temporal, parietal, and occipital lobes, particularly the temporal neocortex
- the left prefrontal cortex subserves working memory for verbal material, and the right prefrontal cortex subserves working memory for nonverbal material
- basal ganglia and cerebellum
- unimodal sensory association areas.
_______ is the most common type of amnesia. It usually affects verbal and nonverbal (visual) materials equally
Anterograde amnesia
Lesion in Korsakoffβs syndrome involves the ________
dorsomedial and midline nuclei of the thalamus, mamillary body, and frontal cerebral cortex.
Immediate and very remote memories are unaffected in________
TGA
__________s a clinical syndrome observed in humans and other animals after bilateral lesions in the temporal lobe that involve the amygdala, hippocampal formation, and adjacent neural structures.
The KlΓΌver-Bucy syndrome
Visual agnosia or psychic blindness (inability to differentiate between friends, relatives, and strangers).
Hyperorality (tendency to examine all objects by mouth).
Hypersexuality (normal as well as perverted sexual activity). Such patients and animals manifest heightened sexual drives toward either sex of their own or other species and even inanimate objects.
Docility.
Lack of emotional response, blunted affect, and apathy
.
Increased appetite, bulimia.
Memory deficit.
Kluver Bucy
The neuropathology consists of a severe focal necrotizing process with a predilection for the limbic system
HSV encephalitis
A brain biopsy of HSV is diagnostic in showing characteristic intranuclear viral inclusions ) ________ and inflammation
(Cowdry type A inclusions)