limbic system

Question 1

wernicke-korsakoff syndrome

Answer 1

major causes is vitamin B1 deficiency and alcoholism

Question 2

where is the damage that results in wernicke-korsakoff syndrome

Answer 2

mammillo-thalamic tract disruption

Question 3

symptoms of wernick-korsakoff syndrome

Answer 3

no new memories
loss of memory
hallucinations
confabulation

Question 4

what is the function of hippocampus

Answer 4

memory consolidation
motivation
location

Question 5

where is the hippocampus?

Answer 5

in the medial temporal lobe

Question 6

what are the three major division of the hippocampus?

Answer 6

dentate gyrus
CA3 (cornus ammon 3)
CA1 (cornus ammon 1)

Question 7

major afferent of hippocampus?

Answer 7

perforant path

Question 8

major efferent of hippocampus?

Answer 8

fornix

Question 9

what is the intrinsic function of hippocampus?

Answer 9

trisynaptic circuit

Question 10

trisynaptic circuit path

Answer 10

entorhinal cortex->perforant path->dentate gyrus->mossy fibers->CA3-> schaffer collaterals->CA1-> subiculum

Question 11

two branches of the fornix

Answer 11

post commissural (circuit of papez) most goes here
pre commissural

Question 12

limbic amnesia

Answer 12

bilateral medial temporal lobe damage

damage mostly in hippocampus

Question 13

signs of limbic amnesia?

Answer 13

cannot form new memories

can recall prior events

Question 14

causes of limbic amnesia?

Answer 14

herpes
head trauma
stroke
epilepsy
drugs
surgery

Question 15

early stages of alzheimer’s disease signs

Answer 15

amnestic
reduced motivation
troubles navigating familiar places
general cognitive impairment

Question 16

three major divisions of the amygdala

Answer 16

basolateral complex
corticomedial
central necleus

Question 17

what are the two major efferents of the amygdaloid complex

Answer 17

amygdalofugal

stria terminalis

Question 18

what is the function of basolateral complex

Answer 18

modulates motor function

Question 19

what are the efferents of the basolateral complex?

Answer 19

amygdalofugal fibers to frontal cortex, basal ganglia, motor cortex

Question 20

what is the function of the corticomedial and central nucleus?

Answer 20

autonomic functions

Question 21

what is the efferent of the corticomedial and central nucleus?

Answer 21

stria terminalis to septal nuclei, autonomics, hypothalamus

Question 22

amygdala signs

Answer 22

poor conditioned emotional response
poor recognition of fear, especially facial
**default is to be afraid

Question 23

what is the cause of Kluver-Bucy syndrome?

Answer 23

bilateral lesions to the amygdala due to trauma, herpes, tumors

Question 24

what are symptoms of Kluver-Bucy syndrome?

Answer 24

docility, overeating, hyperphagia (eating inapporpriate objects) eg: pica, hyperorality, hypersexuality, visual agnosia

Question 25

circuit of papez starts at cingulate gyrus and goes where?

Answer 25

via the cingulum goes to entorhinal cortex

Question 26

from the entorhinal cortex what is next in the circuit of papez?

Answer 26

via the perferant path to the hippocampus

Question 27

from the hippocampus where to the efferents go?

Answer 27

the fornix to the mammillary bodies

Question 28

mammillary bodies send information via the mammallo-thalamic tract to where?

Answer 28

anterior thalamus

Question 29

the anterior thalamus uses the thalamo-cortical tract to send efferents where?

Answer 29

the cortex