Limbic System Flashcards

1
Q

What does limbic system consist of?

A

Hypothalamus
Thalamus
Brain stem reticular formation
Epithalamus
Olfactory cortex
Prefrontal cortex

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2
Q

What does limbic lobe consist of?

A

Septal area
Cingulate gyrus
Parahippocampal gyrus w hippocampus and amygdala, uncus

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3
Q

Components of hippocampal formation?

A

Part of hippocampal gyrus
Hippocampus
Dentate gyrus
Subiculum

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4
Q

Afferents of hippocampal formation?

A

Entorhinal area of the parahippocampal gyrus
Contra lateral hippocampus via the hippocampal comissure
Amygdala
Thalamus
Locus coerulueus
Raphe nuclei
Ventral tegmental area

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5
Q

Efferents of hippocampal formation?

A

Via the fornix to the septal area and the mammillary bodies of the hypothalamus (mammillary bodies project to anterior nucleus of the thalamus which in turn projects to the cingulate gyrus)

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6
Q

What is function of hippocampal formation?

A

Learning and memory and passage of short term memory into long term. Map of spatial memory.

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7
Q

What happens if you lesion hippocampal formation?

A

Defects in explicit memory and spatial orientation.

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8
Q

Explicit (declarative memory)

A

Episodic, semantic (facts).
Medial temporal lobe.

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9
Q

Implicit (non-declarative memory)

A

Priming (neocortex)
Procedural (skills and habits, striatum)
Emotional responses to associative learning (amygdala)
Musculoskeletal responses to associative learning (cerebellum)

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10
Q

Types of amnesia?

A

Retrograde
Anterograde
Global
Modality specific

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11
Q

Amygdala afferents?

A

Autonomic
Sensory
Auditory
Visual information converges here

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12
Q

Amygdala efferents?

A

Via stria terminal is to septal nuclei and hypothalamus, brainstem, and cortex

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13
Q

What is function of amygdala?

A

Affective perception of sensory stimuli. Stimulation results in intense feeling of fear and possibly accompanied by disagreeable olfactory hallucinations

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14
Q

What happens if amygdala is lesioned?

A

Diminished capacity for fear conditioning

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15
Q

What is Kluver Bucy Syndrome?

A

Bilateral experimental lesion of monkey temporal lobes including amygdala and hippocampal formation.

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16
Q

Kluver Bucy Syndrome results in what?

A

Visual agnosia (psychic blindness)
Hyperorality
Hypersexuality
Docility
Apathy
Bulimia
Memory deficit

17
Q

What is Korsakoff’s psychosis?

A

Thiamine deficiency seen sometimes in severe alcoholism that results in anterograde and progressively retrograde amnesia

18
Q

Septal area afferents and efferents of hippocampus?

A

Via fornix, amygdala via stria terminalis, hypothalamus, midbrain, habenula via stria medullaris thalami, thalamus, cingulate gyrus

19
Q

Septal area functions in what?

A

Emotional behavior, stimulation of area results in transient rage and increased water consumption and a reward reaction