lids and lashes Flashcards
give pathological conditions that affect pigmention of eye lashes
poliosis
give pathological conditions that affect direction and position of eye lashes
-trichiasis
-distichiasis
give pathological conditions that affect growth of eye lashes
-hypotrichosis
-hypertrichosis
-milphosis
-madarosis
what is pthiriasis and what is it caused by?
its an infestation of the lid margins by the crab louse phthirus pubis.
give 2 predisposing factors for phthiriasis
Sexual contact with a louse-infested individual
Can be contracted within families through poor hygiene and close
contact
give 3 symptoms of phthiriasis
Intense itching of lid margins
Red watery eye
Unilateral or bilateral
give 8 signs of phthiriasis
madarosis (loss of lashes)
blepharoconjunctival hyperaemia and oedema
superficial punctate keratopathy (SPK)
bites leave red inflamed areas on lid margins (petechial macules)
possible pre-auricular lymphadenopathy (swelling of lymph nodes behind the ears as a result of eye infection)
adult lice (1.0–1.5mm long) attached to lash; almost completely
transparent (high magnification [x40] required at slit lamp)
eggs (termed nits) in greyish white cigar-shaped shells (0.5mm long)
attached near base of lashes. Empty shells remain after hatching
reddish-brown deposits at the base of the lashes are a mixture of louse
faeces and host blood following louse bites
what are some differential diagnoses of phthiriasis?
-blepharitis
-allergic or infective conjunctivitis
-eczema affecting lid skin
how can optoms manage phthiriasis non-pharmacologically?
Sensitive counselling (i.e. by GP) required as this is a sexually
transmitted disease
advice on personal hygiene: wash hands after touching pubic region
NB possibility of sexual abuse of children
Remove lice, nits and shells (casts) at slit lamp
use forceps (lice have a tenacious grip on the lashes)
Advise on any symptoms of pubic infestation
effective treatments (e.g. malathion, permathrin) available without
prescription from pharmacies
Sexual partners or family members at risk should have their eyes
examined and treated if necessary
Bed linen, towels and clothes should be washed at 60°C for at least 5
min
how can optoms manage phthiriasis pharmacologically?
-apply unmedicated paraffin-based ointment like Simple Eye Ointment to lid margins to suffocate the lice
-apply permethrin 1% lotion to lashes for 10 mins with eye closed and then rinse to remove (insecticides are toxic to cornea)
-Referral via GP for management of non-ocular aspects, including tracing and screening close contacts; also screening for other sexually transmitted diseases
what patients does does demodex mite infestation occur more commonly in?
-those with rosacea
-older patients
what skin diseases could be caused by demodex mite infestation?
pityriasis folliculorum
perioral dermatitis
scabies-like eruptions
facial pigmentation
eruptions of the bald scalp
demodicosis gravis
basal cell carcinoma
which 2 demodex species have been found to cause blepharitis? what can they cause?
-in the eyelids, D. folliculorum can be found in the lash follicle: anterior
blepharitis associated with disorders of eyelashes
-D. brevis burrows deep into sebaceous glands and meibomian gland looking for sebum which is thought to be their main food source: posterior blepharitis with meibomian gland dysfunction and keratoconjunctivitis
what are some treatments to control demodex mites?
-use of treatments like mercury oxide 1% ointment, pilocarpine gel, sulfer ointment and camphorated oil
-tea tree oil treatments with eitehr 50% lid scrubs or 5% lid massages to eradicate mites and reduce ocular surface inflammation
what is trichiasis?
Inward misdirection of eyelashes towards the ocular surface,
what are the three types of trichiasis?
Congenital - due to failure of epithelial germ cells to differentiate
completely to Meibomian glands; autosomal dominant inheritance
Acquired - entropion of any cause
what can trachomatous trichiasis cause?
recurrent inflammation of the tarsal conjunctiva which leads to:
-entropion
-trichiasis
-potentially blinding corneal opacification
give an example of an acquired trichiasis
Trachomatous trichiasis: multiple infections with Chlamydia trachomatis
what can trichiasis be secondary to
-severe chemical burn
-eyelid laceration
-stevens Johnson syndrome
-ocular cicatricial pemphigoid
-chronic blepharoconjunctivitis
predisposing factors include:
-trachoma
-staphylococcal blepharitis
what are the symptoms of trichiasis?
May affect one or both eyes
Ocular discomfort, irritation, foreign body sensation
(NB: in the elderly and in people with diabetes, corneal sensitivity may
be reduced)
Watery eye
Red eye
Photophobia
what are the signs of trichiasis?
Lash or lashes in contact with ocular surface
Conjunctival injection
Epiphora
Corneal and/or conjunctival epithelial abrasion (stains with fluorescein)
what are the possible complications of trichiasis?
pannus (corneal neovasc)
corneal ulceration and scarring
what are the differential diagnoses of trachiasis?
Other causes of ocular irritation / red eye
Trichiasis should be differentiated from distichiasis, in which an extra
row of lashes grows from the Meibomian gland orifices
how can you manage trichiasis non-pharmacologically?
Epilation: remove lash(es) with forceps. Advise patient that lash(es) will
re-grow within 4-6 weeks, therefore epilation may need to be repeated
If due to entropion, tape the eyelid for temporary relief of symptoms
Consider therapeutic contact lens (silicone hydrogel soft, rigid mini-
scleral or scleral) for temporary relief of symptoms
Lid hygiene for associated blepharitis
how can you manage trichiasis pharmacologically?
-ocular lubricants for symptomatic relief
-surgical intervention for more severe cases with complications so do initial management and then urgent referral to secondary care
for squamous papillomas, what are they, how would you treat them?
-flesh-coloured growths
consisting of squamous hyperplasia within the epithelium.
-Removal by simple excision may be performed for cosmesis or effects on
vision
what are the two types of squamous papillomas?
-sessile (broad based attachment)
-pedunculated (on a stalk)
for seborrheic keratosis, what kind of individuals does it affect?
older people
for seborrheic keratosis, what causes them?
They develop from intradermal proliferation of basal cells within the epidermis
for seborrheic keratosis what is it and how can it be treated?
-benign elevated, pigmented, crusty, greasy, stuck-on plaques (sudden increase in number or size could indicate malignancy)
-complete excision
what are epidermal inclusion cysts and what is the treatment?
-are slowly enlarging keratin filled cysts. –
-They can be removed by excision and curettage
what is verruca vulgaris? (viral wart)
epidermal growth caused by the human
papilloma virus that starts as small papules slightly lighter than the surrounding skin which darken and become hyperkeratotic with time
what are the two types of verruca vulgaris?
-filiform/ digitate = project in a finger-like nature from their base
-plana = flat in appearance
what can verruca vulgaris on the eyelid margin cause?
-punctate keratitis
-corneal pannus
how does verruca vulgaris tend to be self limiting, how can you otherwise treat it?
as these lesions tend to eventually outgrow their blood supply and spontaneously involute.
-excision
-cryotherapy
-chemical cautery
what is molluscum contagiosum, who does it more commonly affect, what can it cause?
-small, typically 1mm to 2mm, flesh-coloured papules often with an umbilicated centre.
-very young and immunocompromised patients
-can cause follicular conjunctivitis and are spread by skin-to-skin contact.
what is a pyogenic granuloma, what are they made of, what are they caused by?
-a pinkish or red, rapidly growing vascularized mass that protrudes from the conjunctiva that bleeds with minor insults
-made of blood vessels and fibroblasts
-response to local trauma
what are ephelides?
freckles, in terms of the eye can be present on the lid margins
what are sebaceous/ pillar cysts caused by? What 3 places might they arise from?
blocked pilosebaceous follicles containing
sebum.
-glands of zeis within the eyelashes
-meibomian glands
-from sebaceous glands associated with hair follicles
name 2 premalignant lesions that that can occur on the lids
-Actinic keratosis
-keratoacanthomas
what is actinic keratosis?
pink/red/brown scaly lesion common
on sun-exposed areas of the skin such as the face, scalp, and hands.
what is keratocanthomas? who does it most commonly affect? how do you manage it?
- Rapidly growing papules with a central keratin-filled core
- most commonly affects elderly or immunocompromised individuals
-can resolve by itself after several months but complete excision is normally recommended due to risk of it becoming squamous cell carcinoma
what is eyelid twitching called? what actually causes it to happen? when does it tend to arise?
-eyelid myokymia
- repetitive muscle contractions affect the
muscle of Müller and the ciliary part of the orbicularis oculi, causing
twitching or flickering.
-tends to arise when he px has periods of stress, fatigue, excessive caffeine consumption or asthenopia
how can you confirm eyelid myokymia diagnosis?
-episodic nature
-localized to lids
-painless
-no functional impairment
how can you treat eyelid myokymia?
-rest
-cold compress
-tonic water
-stress reduction
-botulinum toxin in cases of excessive twitching
what is the order of layers that make up the eyelid from outer to inner?
-skin =
-orbicularis oculi
-tarsal plate
-conjunctiva
what part of the eyelid are meibomian glands?
in the tarsal plate
what does the sebaceous tissue in the skin of the eyelids contain?
-Eyelashes
-Ciliary glands of moll: sweat glands
-Glands of zeis: sebaceous glands
give 4 eyelid malpositions
- Ectropian
- Entropian
- 7th Nerve Palsy
- Ptosis
what is ectropion? How can you diagnose it?
where the eyelid turns outwards
diagnosis with:
-the snap back test where you pull the eyelid and if it doesn’t snap back then its ectropion
-fluorescein instillation and then observe under slit lamp
what are the symptoms of ectropion?
sore, red and watery eyes
what can cause ectropian?
scarring or contracture of skin/ underlying tissue which causes the eyelid to pull away from the globe and this can be:
-involutional
-cicatrical
-paralytic - nerve palsy
-mechanical
-congenital
how do you manage someone with ectropian?
treat the symptoms and then do a routine referral
what are the symptoms of entropian?
-foreign body sensation
-blurred vision
-redness
-irritation
how do you diagnose entropion?
-ask the px to look down while you hold their upper lid and the entropion is induced
-SL and fluorescein
what are the signs of entropion?
-corneal scarring
-corneal ulcer (rare)
-conjunctival staining with fluorescein
how can you treat entropion
-artificial tears
-lid taping
-routine referral
what is and what can cause entropion?
when scarring of the palpebral conjunctiva can rotate the upper or lower lid margin towards the globe:
Causes:
cicatrizing conjunctivitis
trachoma
trauma
chemical injuries
what are the symptoms of 7th nerve palsy?
-watery eyes
-unilateral
-facial muscle weakness
what are the signs of 7th nerve palsy?
-dry eye
-sagging of eyelid/ corner of mouth
-drooping of eyebrow
how can you manage 7th nerve palsy?
-GP referral (gp may give steroids/ antivirals due to possible cause of viral infections like herpes simplex
-artificial tears
what can cause a ptosis?
-congenital
-3rd nerve palsy
-eye tumour
-diabetes / stroke
-age
when would you have to refer a lid ptosis?
if they patient wanted to correct it with surgery
name 4 benign lid lesions
-chalazion
-hordeolum
-cysts of zeis/ moll
-papilloma
name 4 malignant eyelid lesions
-BCC
-SCC
-Sebaceous carcinoma
-Malignant melanoma
what are the signs of a ptosis?
drooping of upper eyelid
does chalazion have symptoms?
no - painless
what are the signs of a chalazion?
-well defined lump- usually on upper eyelid
-granuloma (white head like dot) when you invert the eyelid
what causes a chalazion?
blocked MG
how can you manage a chalazion?
warm compress and massage 1-2 times a day for a few weeks - should go away on its own
what are the symptoms of a hordeolum?
a tender lump on the inner/outer eyelid
what causes a hordeolum?
bacterial infection
how can you manage a hordeolum?
warm compresses daily, chloramphenicol 1% ointment
what are the 2 types of hordeolum?
-internal hordeolum which is infection of the tarsal plate
-outer hordeolum is a bacterial infection of the lid margin
what are the predispositions of hordeolum?
-blepharitis
-rosacea
-dermatitis
-diabetic patients
what are the symptoms of basal cell carcinoma?
slowly developing painless lump
what are the signs of bcc?
nodules on the lower lid
what causes bcc?
sun exposure (UV)
How can you manage bcc?
urgent referral so it can be removed in surgery
what are the symptoms of scc?
rapid, painful growth
what are the signs of scc?
scaly raw lesion on the lower lid
what can cause scc?
actinic keratosis and UV