Lice, Scabies, Spider Bites Flashcards
Pediculosis
- What are they?
- What is head lice called?
- What is body lice called?
- Ectoparasites that live on the body and feed on human blood after piercing the skin.
- Pediculosis capitus: head lice
- Pediculosis corporis: body lice
Pediculosis
Clinical presentation?
3
- Pruritus
- May take 2-6 weeks to develop after first exposure - Itching and scratching can lead to secondary cellulitis
- Pubic lice should prompt evaluation for other sexually transmitted infections
Pediculosis
Dx? 3
- Observation of:
Eggs (nits)
Nymphs
Mature lice - Commonly found behind ears and on the back of the neck
- Wood lamp of area
Yellow-green fluorescence of lice/nits
Pediculosis Treatment
1. Medication: Focus on two mechanisms? (which drugs go with these mechanisms?)
Medication Focus on 2 mechanisms 1. Neurotoxicity -Permethrin 1% lotion (Nix) first-line 2. Suffocation via “coating” -Benzyl alcohol 5% lotion (Ulesfia)
Which drug promotes hyperexcitation and death by paralysis?
Spinosad 0.9% (Natroba)
Environmental control
Treat all persons who have contact with infested patients (especially who?
Sexual partners
Sarcoptes Scabiei (Scabies)
1. What is it?
2. How do we find them?
2
- Contagious infection caused by the mite Sarcoptes Scabiei.
- Tiny and usually not directly visible
- Parasite that burrows under the host’s skin causing intense itching
Sarcoptes Scabiei (Scabies)
- May be transmitted from _____?
- Most often transmitted by what?
- Spread rapidly under crowded condition such as? 4
- Usually symptomatic after how long?
- May be transmitted from objects
- Most often transmitted by direct skin to skin contact
Higher risk with prolonged contact
- Spread rapidly under crowded conditions
- Nursing homes
- Extended care facilities
- Prisons
- Child care facilities - Usually two to six weeks before become symptomatic
Sarcoptes Scabiei (Scabies)
- Common sites of mites?
- Common sites of rash? 7
- Creases in skin
- Axilla
- Stomach
- Genitals
- lower back/buttocks
- elbows
- knees
- upper back
Sarcoptes Scabiei (Scabies) Classic scenario:
Itching:
- Caused by what?
- May be worse with what?
- Worse when?
- Watch for what?
- Caused by allergic reaction to the mites.
- Made worse by warmth
- Usually worse at night
- Watch for excoriation
Scabies
Types of lesions?
5
- Burrow- linear tunnel in which the mites live
- Papules
- blisters
- nodules
- eczematous
Scabies
Dx?
2
- Scraping off a tiny bit of skin
2. View under a microscope for mites or eggs
- Scabies treatment
- Apply where?
- Leave on for how long?
- Repeat when if necessary?
- Safe for children as young as what?
- SE? 4
- Treat who else? 2
- Permethrin Cream 5% 60 gram tube (preferred treatment)
- Apply from head to feet
- Leave on for 8-14 hours then wash with soap and water
- Repeat in 7 days if necessary
- Safe for children as young as 1 month old and pregnancy
- Side effects:
- Mild to moderate burning and stinging
- Itching
- Rash
- Redness - Treat family members and sexual partners
Scabies treatment
Alternate medications? 2
- Lindane Lotion 1%
2. Oral Ivermectin
Lindane Lotion 1%
- Disadvantage?
- Most pts require what?
Oral Ivermectin
- Dosing?
- Do not use in who? 2
Lindane Lotion 1%
- Has more neurotoxicity than Permethrin
- Most patients require 30ml but larger adults up to 60ml
Oral Ivermectin
- 200mcg/kg by mouth as single dose with repeat dose in two weeks
- CDC recommends not using in pregnant or lactating women
Scabies
Can give something for the itching? 3
Watch for what?
- Atarax (Hydroxyzine) 10-25mg po every 4-6 hrs prn itching
- Benadryl 25mg po every 4-6 hrs prn itching
- Steroid cream
Secondary infections
- How do spiders cause infection?
2. Which spiders are most likely to inflict medically significant bites? 2
- Use sharp fangs to bite prey and inject venom
Spider bites:
Rare medical events
Most pose no threat to humans
- Spiders most likely to inflict medically significant bites
- Widow
- Recluse
Common disorders can mimic a spider bite
- How do widow spider bites look?
- What do they release?
Recluse
- Notorious for becoming what?
- What kind of reaction do they cause?
- What toxin do they release?
- Genus?
- Unremarkable local lesions
- Characteristic systemic reaction - Neurotoxin
α- latrotoxin - Notorious for becoming necrotic (rare)
- Systemic reaction mild
- Nonspecific signs and symptoms - Sphingomyelinase D
- Latrodectus genus
Spider bites: Acute lesions can be what? 3
- Papule
- Pustule
- Wheal
Widow spiders
Patient History
Recent less than 8hrs at risk activity
5
- Gardening
- Chopping wood
- Using outdoor furniture
- Cleaning a garage
- Moving into a house that has not been occupied recently
Widow Spiders History findings?
3
- Bite usually on the extremities (especially lower)
- Most are initially asymptomatic or cause mild pain at the site
- Muscle pain is the most prominent feature in systemic reactions
Muscle pain is the most prominent feature in systemic reactions.
How does it manifest?
3
Other symptoms may include? 3
- Extremity muscles
- Abdomen
- Back
- Tremor
- Weakness
- Shaking of the extremity
Presentation of infants and children for widow bites?
4
- Nonspecific
- Distressed and inconsolable
- Refusing food and drink
- Generalized erythema
Widow bites: Physical findings?
5
- Vital signs normal in 70% of patients
Musculoskeletal exam:
2. Intermittent muscle rigidity and
- tenderness adjacent to the bite
OR abdomen, chest or back - Weakness, tremor, and myoclonus
- Diaphoresis:
Corresponds to affected muscle group
Widow Physical findings:
Wound site & local symptoms 5
- Blanched circular patch
- Surrounding red perimeter
- Central punctum
- Appears like a “target” lesion
- 50 percent of cases
Widow bite Dx
1. Primarily based on what?
- Possible lab studies? 3
- Adults with cardiac risk factors consider? 2
- Primarily based on symptoms and signs with history
- No specific lab studies
- Leukocytosis
- Elevated creatinine
- Elevated Liver enzymes - Adults with cardiac risk factors consider:
- EKG’s
- Cardiac enzymes
DDx for Widow bites? 6
- MRSA
- Surgical abdomen
- Lyme
- Myocardial ischemia or infarction
- Tetanus
- Rabies
Envenomation
Mild presentation? 2
Moderate presentation? 4
Severe? 3
Mild
- Localized pain at bite
- Normal vital signs
Moderate
- Muscular pain in envenomated extremity
- Extension of muscular pain to chest or abdomen
- Local diaphoresis at bite
- Normal vital signs
Severe
- Generalized muscular pain in back, abdomen and chest
- Diffuse diaphoresis
- Abnormal vital signs
Mild Envenomation treatment?
4
- Local measures: Gently clean the bite with mild soap and water
- Oral analgesia:
- Oral muscle relaxers:
- Tetanus prophylaxis if indicated
Mild Envenomation treatment:
1. What would you use for oral analgesia?
3
- What would you use for oral muscle realxers? 2
- Acetaminophen
- Ibuprofen
- Oxycodone or hydrocodone
- Benzodiazepines (Valium)
- Methocarbamol (Robaxin)
Moderate to Severe Envenomation treatment?
5
- Local wound care and tetanus prophylaxis as for mild envenomation
- Parenteral opioids (e.g. morphine)
- Parenteral benzodiazepines (e.g. lorazepam) to reduce the frequency and severity of muscle spasms
- Antiemetic therapy (e.g. Sublingual or intravenous ondansetron)
- Consider Antivenom administration
- Consult with medical toxicologist prior to administration
- Carries small risk of anaphylactic reactions
Brown Recluse
- Where do you usually sustain the bite?
- Typically appear where? 3
- Notorious for what?
- FOund where? 3
- Produces what?
- Genus?
- Bites are usually sustained indoors
- Typically on
- upper extremities,
- thorax or
- inner thigh - Notorious for sometimes causing skin necrosis
- South, West, and Midwest areas
- Cytotoxic enzymes
- Loxosceles
- Brown recluse local symtpoms? 4
2. Systemic? 4
Local Symptoms:
- Usually develop two to eight hours after a bite.
- Usually painless initially
- Occasionally some minor burning that feels like a bee sting
- Severe pain at bite site after about four hours
Systemic symptoms:
- Malaise
- Nausea & Vomiting
- Fever
- Myalgias
Brown Recluse physical findings?
5
- Initially bite site is mildly red
- May reveal fang marks
- Blistering (common)
- Necrosis of skin and subcutaneous fat (less common)
- Severe destructive necrotic lesions with deep wide borders (rare)
Brown Recluse Dx?
Based on? 2
Definitive Dx? 2
If both these conditions are not met what must you do?
- Based most often on:
- History
- Clinical presentation - Definitive:
- A spider was observed inflicting the bite
- Spider recovered, collected, and properly identified by an expert entomologist - If both conditions are not met, then other conditions must be excluded.
Brown Recluse DDx?
10
Numerous conditions mistaken for recluse spider bite
- Bacterial
- Deep fungal
- Pseudomonas aeruginosa
- Parasitic
- Viral
- Topical and exogenous causes
- Venous
- Neoplastic disease
- Necrotizing vasculitis
- Diabetic ulcers
Brown recluse treatment
5
- Local wound care
- Pain management with
NSAIDS or opioids if necessary - Tetanus prophylaxis if indicated
- Dapsone in some cases to prevent progression to necrosis & reduce pain
- No Antivenom available in the United States
What would you do for local wound care for a brown recluse?
3
- Clean with mild soap and water
- Apply cold packs
- Maintain affected part in elevated or neutral position