LFTs

Question 1

ALT role

Answer 1

enzyme that helps to process proteins

Question 2

ALT raises

Answer 2

when liver is injured or inflamed

Question 3

when is AST suggestive of liver disease?

Answer 3

> 500

Question 4

why is AST less useful?

Answer 4

can also be raised in heart or skeletal muscle damage

Question 5

where is ALP?

Answer 5

mainly in liver cells next to bile ducts

Question 6

when is ALP raised?

Answer 6

in some types of liver and bone disease

Question 7

albumin

Answer 7

main protein made by liver that circulates in the bloodstream

Question 8

total protein

Answer 8

measures albumin and other proteins in the blood

Question 9

elevated bilirubin

Answer 9

prognostic marker for ALD

Question 10

blood clotting test

Answer 10

prothrombin time

time it takes for liver to produce the proteins needed to make blood clot

Question 11

GGT

Answer 11

longstanding alcohol abuse

low sensitivity and specificity

Question 12

reduced ceruloplasmin

Answer 12

wilsons

Question 13

lack of A1- antitrpysin

Answer 13

can cause cirrhosis

Question 14

high levels of ferritin

Answer 14

haemachromotosis

Question 15

decreased albumin

Answer 15

prognostic marker for ALD

Question 16

prolonged INR

Answer 16

prognostic marker for ALD