Leys - Vitamins Flashcards
Measurements of vitamin levels in the blood relate more to _______ than to _______.
recent intake
overall body status
_______ act as _______ in many metabolic pathways.
water-soluble vitamins
coenzymes
The body has no storage capacity for _______ except _______.
water-soluble vitamins
B12
Evidence is emerging that suggests an excess of some _______ can be toxic.
B vitamins
Most vitamins are _______ before they become _______.
modified
active
B vitamins are co-enzymes in different types of reactions: \_\_\_\_\_\_\_ - \_\_\_\_\_\_\_ \_\_\_\_\_\_\_ - \_\_\_\_\_\_\_ \_\_\_\_\_\_\_ - \_\_\_\_\_\_\_ \_\_\_\_\_\_\_ - \_\_\_\_\_\_\_ \_\_\_\_\_\_\_ - \_\_\_\_\_\_\_
B1 - carboxylations B2/B3 - oxidoreductases B6 - transaminases biotin - carboxylases folic acid/B12 - single carbon transfers
Lack of _______ causes _______.
riboflavin
angular stomatitis
Eating _______ can cause a _______ deficiency.
raw egg whites
biotin
_______ is needed, indirectly, for DNA synthesis.
folic acid
_______ are used as antibiotics (trimethoprim) and cancer therapy (methotrexate).
inhibitors of folate reduction
There is an increased demand for _______ during pregnancy.
folic acid
_______ deficiency is one of the most common vitamin deficiencies.
folic acid
The functions of _______ and _______ are interrelated.
B12
folic acid
_______ is concentrated in the liver.
B12
_______ deficiency causes scurvy resulting in _______.
vitamin C
defective collagen synthesis
Lack of _______ also impairs immune function.
vitamin C
_______ vitamins are not as readily absorbed as _______ vitamins, but can be stored in _______.
fat-soluble
water-soluble
tissues
Some _______ vitamins (_______ and _______) can be toxic in excess.
fat-soluble
A
D
_______ is _______ and should be avoided during pregnancy.
vitamin A
teratogenic
_______ is a signaling molecule that interacts with _______.
retinoic acid
ligand-activated transcription factors
Deficiency of _______ causes night blindness.
vitamin A
_______ regulates calcium and phosphorous homeostasis.
vitamin D
The majority of _______ is produced by _______ of skin.
vitamin D
UV exposure
People in northern climates have a difficult time getting sufficient _______ in the winter.
vitamin D
Deficiency of _______ causes _______ of bones with _______ susceptibility to fractures.
vitamin D
demineralization
increased
_______ deficiency is a link to childhood caries.
vitamin D
_______ is necessary for blood coagulation.
vitamin K
Which type of vitamin (water-soluble or fat-soluble) acts as coenzymes in many metabolic pathways?
water-soluble
Which type of vitamin (water-soluble or fat-soluble) is less readily absorbed through the diet?
fat-soluble
Which type of vitamin (water-soluble or fat-soluble) can be stored in tissues?
fat-soluble
What is the only water-soluble vitamin to be able to be stored?
vitamin B12
What is the only fat-soluble vitamin to act as a coenzyme?
vitamin K