Levetiracetam (CALL FOR CCP BACK UP!)

Question 1

What is the mechanism of Levetiracetam

Answer 1

Anticonvulsant. Believed to terminate seizure activity by blocking some calcium channels and binding synaptic proteins to modulate neurotransmitter release.

Question 2

What is the indication for Levetiracetam?

Answer 2

Seizures that continue after two doses of parental Midazolam.

Question 3

What are the contraindications of Levetiracetam?

Answer 3

●Known severe allergy.

Question 4

What are the cautions for Levetiracetam?

Answer 4

There are none.

Question 5

What is the adult IV dose of Levetiracetam?

Answer 5

●2g. Repeat once after 10mins if seizure occurs.
Administer into a running line over 5mins.

Question 6

What are the side effects of Levetiracetam?

Answer 6

●There are none.

Question 7

What is the onset time for Levetiracetam?

Answer 7

10mins.

Question 8

What is the duration of effect for Levetiracetam?

Answer 8

6-8 hours.

Question 9

What is the preparation of Levetiracetam?

Answer 9

Ampoule containing 500mg/5ml.
Draw up x4 ampoules (2g/20ml) and dilute to 40ml.
Administer over 5 minutes.