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HEMA FINALS > leukemia disorder > Flashcards

leukemia disorder Flashcards

1
Q
  • are generalized neoplastic proliferation or
    accumulation of leukopoietic cells with or without
    involvement of the peripheral blood.
A

LEUKEMIAS

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2
Q

based on natural history

A

Chronologic

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3
Q

the most common form of leukemia in children

characterized by a rapid increase in the numbers of
immature blood cells

A

Acute Leukemia

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4
Q

characterized by the excessive build up of relatively
mature, but still abnormal, white blood cells
- mostly occurs in older people, but can theoretically
occur in any age group

A

Chronic Leukemia

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5
Q

lasting from two to six months or even twelve
months

A

Sub-acute Leukemia

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6
Q

a type of myeloblastic leukemia

formation of tumors originating from periosteum,
especially of skull, orbits, nasal sinuses, ribs and
vertebrae

A

Chloroma

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7
Q

a focal malignant tumor composed of myeloblast
or early myeloid precursors occurring outside of the
bone marrow

A

Myeloblastoma

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8
Q

local tumorous proliferation of plasma cells in the
marrow

A

Myeloma

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9
Q

presence of immature or abnormal cells with WBC
count greater than 15 x 10⁹/L

A

Leukemic Leukemia

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10
Q

with immature or abnormal cells in peripheral
blood and with WBC count less than 15 x 10⁹/L

A

Subleukemic Leukemia

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11
Q

with no immature cells in the peripheral blood and with WBC count less than 15 x 10⁹/L

A

Aleukemic Leukemia

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12
Q

is a reactive but excessive leukocytosis
characterized by the presence of immature cells in
the peripheral blood vessels

A

Leukemoid Reactions

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13
Q

group of neoplasms characterized by proliferation of
myeloid tissue and elevation in one or more myeloid
cell type in the peripheral blood

A

Myeloproliferative Disorders

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14
Q

other name of Myelofibrosis

A

Myeloid Metaplasia

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15
Q

hematopoietic cells is the

A

Philadelphia
chromosome

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16
Q

are group of clonal disorder of neoplastic
pluripotential stem cells characterized by a decrease
in one or more types of peripheral blood cells due to
abnormal maturation in the bone marrow

A

Myelodysplastic syndrome

17
Q

represent a group of neoplastic conditions
originating from cells of the lymphoreticular system

A

Lymphoproliferative Disorders

18
Q

composed of small B-lymphocytes with abundant cytoplasm and fine cytoplasmic projections

A

Hairy Cell Leukemia

19
Q

Classical Hodgkin lymphoma

A

Hodgkin’s Disease

20
Q

a malignant disorder characterized by painless,
progressive enlargement of lymphoid tissue

A

Hodgkin’s Disease

21
Q

nucleus bearing a very large nucleolus

A

Reed-Sternberg Cell

22
Q

has an “owl’s eye”
appearance or popcorn appearance

A

Reed-Sternberg

23
Q

represent a group of diseases with abnormal
proliferation of mesenchymal cells that are closely
related to phagocytic histiocytes and to fat cells

A

Storage Disease

24
Q

other name of Multiple Myeloma

A

Plasmatocytoma
Kohler’s Disease

25
Q

is a neoplasmic proliferation of morphologically
abnormal plasma cells primarily occurring in the BM
either in nodules or diffusely

A

Multiple Myeloma

26
Q

is a collagen disease which affects women most
commonly

A

Systemic Lupus Erythematosus

27
Q

3 types of Antibody

A

a. Anti-DNP
b. Anti-DNA
c. Anti-nuclear

28
Q

a disorder secondary to an infection with the human
immunodefficiency virus (HIV)

A

Acquired Immunodeficiency Syndrome

29
Q

a RNA retrovirus that is cytotropic for CD4
positive T cells and macrophages

A

human
immunodefficiency virus (HIV)

30
Q

other name of Infectious Mononucleosis

A

Glandular Fever
Pfeiffer’s Disease
Kissing Disease

31
Q

based on predominant cell type

A

cytologic

32
Q

CYTOLOGIC (BASED ON PREDOMINANT CELL
TYPE

A
  1. Granulocytic or Myelocytic Leukemia
  2. Lymphocytic/Lymphoid Leukemia
  3. Monocytic Leukemia
  4. Plasma Cell Leukemia
  5. Mast Cell Leukemia
  6. Histiocytic Leukemia
  7. Megakaryocytic Leukemia
  8. Basophilic Leukemia
33
Q

is a neoplastic clonal MPD that commonly
manifests with panmyelosis in the bone marrow and ncreases in RBC, granulocytes, and platelets in the
peripheral blood

A

polycythemia vera

34
Q

classified as a MPD in which the proliferation of an
abnormal type of BM stem cell results in fibrosis, or
the replacement of the marrow with collagenous
connective tissue fibers

A

Myelofibrosis

35
Q

Characterized by autonomous proliferation of the
megakaryocytic cell lines.
*Thrombocytosis is present without a reactive cause.

A

Thrombocythemia

36
Q
A

HEMA FINALS (7 decks)

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