leukemia disorder

Question 1

• are generalized neoplastic proliferation or
  accumulation of leukopoietic cells with or without
  involvement of the peripheral blood.

Answer 1

LEUKEMIAS

Question 2

based on natural history

Answer 2

Chronologic

Question 3

the most common form of leukemia in children

characterized by a rapid increase in the numbers of
immature blood cells

Answer 3

Acute Leukemia

Question 4

characterized by the excessive build up of relatively
mature, but still abnormal, white blood cells
- mostly occurs in older people, but can theoretically
occur in any age group

Answer 4

Chronic Leukemia

Question 5

lasting from two to six months or even twelve
months

Answer 5

Sub-acute Leukemia

Question 6

a type of myeloblastic leukemia

formation of tumors originating from periosteum,
especially of skull, orbits, nasal sinuses, ribs and
vertebrae

Answer 6

Chloroma

Question 7

a focal malignant tumor composed of myeloblast
or early myeloid precursors occurring outside of the
bone marrow

Answer 7

Myeloblastoma

Question 8

local tumorous proliferation of plasma cells in the
marrow

Answer 8

Myeloma

Question 9

presence of immature or abnormal cells with WBC
count greater than 15 x 10⁹/L

Answer 9

Leukemic Leukemia

Question 10

with immature or abnormal cells in peripheral
blood and with WBC count less than 15 x 10⁹/L

Answer 10

Subleukemic Leukemia

Question 11

with no immature cells in the peripheral blood and with WBC count less than 15 x 10⁹/L

Answer 11

Aleukemic Leukemia

Question 12

is a reactive but excessive leukocytosis
characterized by the presence of immature cells in
the peripheral blood vessels

Answer 12

Leukemoid Reactions

Question 13

group of neoplasms characterized by proliferation of
myeloid tissue and elevation in one or more myeloid
cell type in the peripheral blood

Answer 13

Myeloproliferative Disorders

Question 14

other name of Myelofibrosis

Answer 14

Myeloid Metaplasia

Question 15

hematopoietic cells is the

Answer 15

Philadelphia
chromosome

Question 16

are group of clonal disorder of neoplastic
pluripotential stem cells characterized by a decrease
in one or more types of peripheral blood cells due to
abnormal maturation in the bone marrow

Answer 16

Myelodysplastic syndrome

Question 17

represent a group of neoplastic conditions
originating from cells of the lymphoreticular system

Answer 17

Lymphoproliferative Disorders

Question 18

composed of small B-lymphocytes with abundant cytoplasm and fine cytoplasmic projections

Answer 18

Hairy Cell Leukemia

Question 19

Classical Hodgkin lymphoma

Answer 19

Hodgkin’s Disease

Question 20

a malignant disorder characterized by painless,
progressive enlargement of lymphoid tissue

Answer 20

Hodgkin’s Disease

Question 21

nucleus bearing a very large nucleolus

Answer 21

Reed-Sternberg Cell

Question 22

has an “owl’s eye”
appearance or popcorn appearance

Answer 22

Reed-Sternberg

Question 23

represent a group of diseases with abnormal
proliferation of mesenchymal cells that are closely
related to phagocytic histiocytes and to fat cells

Answer 23

Storage Disease

Question 24

other name of Multiple Myeloma

Answer 24

Plasmatocytoma
Kohler’s Disease

Question 25

is a neoplasmic proliferation of morphologically abnormal plasma cells primarily occurring in the BM either in nodules or diffusely

Answer 25

Multiple Myeloma

Question 26

is a collagen disease which affects women most commonly

Answer 26

Systemic Lupus Erythematosus

Question 27

3 types of Antibody

Answer 27

a. Anti-DNP b. Anti-DNA c. Anti-nuclear

Question 28

a disorder secondary to an infection with the human immunodefficiency virus (HIV)

Answer 28

Acquired Immunodeficiency Syndrome

Question 29

a RNA retrovirus that is cytotropic for CD4 positive T cells and macrophages

Answer 29

human immunodefficiency virus (HIV)

Question 30

other name of Infectious Mononucleosis

Answer 30

Glandular Fever Pfeiffer’s Disease Kissing Disease

Question 31

based on predominant cell type

Answer 31

cytologic

Question 32

CYTOLOGIC (BASED ON PREDOMINANT CELL TYPE

Answer 32

1. Granulocytic or Myelocytic Leukemia 2. Lymphocytic/Lymphoid Leukemia 3. Monocytic Leukemia 4. Plasma Cell Leukemia 5. Mast Cell Leukemia 6. Histiocytic Leukemia 7. Megakaryocytic Leukemia 8. Basophilic Leukemia

Question 33

is a neoplastic clonal MPD that commonly manifests with panmyelosis in the bone marrow and ncreases in RBC, granulocytes, and platelets in the peripheral blood

Answer 33

polycythemia vera

Question 34

classified as a MPD in which the proliferation of an abnormal type of BM stem cell results in fibrosis, or the replacement of the marrow with collagenous connective tissue fibers

Answer 34

Myelofibrosis

Question 35

Characterized by autonomous proliferation of the megakaryocytic cell lines. *Thrombocytosis is present without a reactive cause.

Answer 35

Thrombocythemia