lesson 7 pharmacology of the GI tract

Question 1

vomiting

Answer 1

• natural defence
• signals disease/organ dysfunction
• may be involuntary/self induced
• associated with many causes including flu, pregnancy, motion sickness

Question 2

how vomiting works

Answer 2

• vomiting center

- chemoreceptor trigger zone (sends signal to VC) then we start vomiting

Question 3

emesis drugs

Answer 3

• ondansetron (bind to 5-HT receptors blocks stimulation)
• metoclopramide (medulla)
• dimenhydrinate (gravol) (works on CTZ/VC)

Question 4

adverse effects of emesis

Answer 4

• dry mouth
• sedation
• diarrhea
• blurred vision

Question 5

phases of digestion

Answer 5

cephalic
gastric
intestinal

Question 6

phases of digestion cephalic

Answer 6

sight, smell, taste or thought of food stimulates the release of gastric juices

Question 7

phases of digestion gastric

Answer 7

stomach distends more release of gastric juices

Question 8

phases of digestion intestinal

Answer 8

fats and acids prevent the secretion of gastric juices

Question 9

peptic ulcer causes

Answer 9

long term use of NSAIDs

Question 10

peptic ulcer symptoms

Answer 10

heart burn, nausea, vomiting and loss of appetite

Question 11

what does GERD stand for

Answer 11

gastrointestinal esophageal reflux disease

Question 12

GERD

symptoms
causes

Answer 12

heartburn

inappropriate constriction of the lower esophageal sphincter

Question 13

how to treat GERD

Answer 13

antibiotics
antiulcer drug therapy

lose weight/eat healthy/stop smoking/evaluate head of bed

Question 14

what drugs inhibit vomiting

Answer 14

antiemetics