Lessom 23.3 - Adaptive Immune Response Flashcards
A highly specific mechanism of the immune system that recognizes a particular pathogen. Uses cell-surface receptors.
Adaptive Immune System or Adaptive Immunity
Recognition mechanisms of innate immunity
Rapid response (hours)
Fixed
Limited number of specificities
Constant during response
Recognition mechanisms of adaptive immunity
Slow response (days to weeks)
Variable
Numerous highly selective specificities
Improve during reponse
Both innate and adaptive immunity have…
common effector mechanism for the destruction of pathogens
Cells of the Adaptive Immune System
T cells
B cells
Are involved with:
- Activation of phagocytic cells
- Release of chemicals and antigen-specific cells
T cells
Are are involved in:
- Steps that deal with the release of antibodies
B cells
Development of B-cells and T-cells
- Origin- originated from red bone marrow
- Maturation - T cells to-be are migrated from the marrow to the thymus where they mature, while b cells mature in the bone marrow
- Seeding secondary lymphoid and circulation
- Antigen encounter and activation
- Proliferation and differentiation
Steps of the Adaptive Immune Response: Lymphocytes with receptors that can recognize infecting pathogen are selected to participate
Recognition of the infectious pathogen
Steps of the Adaptive Immune Response: T-cells and B-cells are selected based on ________ and ________ selections
Selection of pathogen-specific lymphocytes
- positive
- negative
Steps of the Adaptive Immune Response: Adaptive immune response can be felt mostly a week after the infection started.
Effector Mechanism
Steps of the Adaptive Immune Response
- Recognition of the infectious pathogen
- Selection of pathogen-specific lymphocytes
- Effector mechanism
An Example of an Adaptive Immune Response is __________ virus causes an infection in the ___________. Symptoms can be felt for 3-4 days after infection and will continue to persist for 5-7 days
Influenza
lower respiratory tract
_______________ refers to the body’s ability to quickly recognize and act against an antigen as a response to previous exposure
Immunological memory
____________ is a type of adaptive immunity that provides an immunological memory
Acquired immunity