LES Flashcards

1
Q

Epidemiología

A

Mujer en edad fértil 90%

Relación M:H 9:1

+F y agresiva en Afroamericanos

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2
Q

Etiopatogenia

Hipersensibilidad tipo:

A

HLA-DR3

Radiaciones UV

Estrógenos

Tipo 3!

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3
Q

Manifestaciones clínicas

A

Son generales e inespecíficas

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4
Q

Hipersensibilidad tipo?

A

3

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5
Q

Tipo de nefropatía +F en LES?

A

Tipo IV (Proliferativa Difusa).

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6
Q

Anticuerpos que espero encontrar?

Anticuerpo muy específico, da peor pronóstico y se asocia a nefritis lupica?

A

Anticuerpo antinuclear ANA. 95%

Anti DNA 40-70%!

Anti-Sm son específicos

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