Leqvio Oral Boards- Question 6

Question 1

Risk Enhancing Factors

Answer 1

• Family history of ASCVD
• hypercholesterima
• chronic kidney disease
• ethnicity
• etc.

Question 2

4 categories of risk

Answer 2

low risk- <5%
borderline- 5%-7%
intermediate- 7%-20%
high risk- 20% and above

Question 3

Treatment goal and option

Answer 3

• the goal for treating ASCVD is to get patients LDL-C levels at 70 or lower.
• lifestyle modifications - 10-15%
• pharmalogical approved treatments

Question 4

Pharmalogical Approved Treatments

Answer 4

• Statins - reduction goal of 50%
• Non-statin therapy- reduction rate/ goal depends on which form of treatment. For example, bile salt sequesterant reduces LDL-C levels 15-30%
• PCSK9 Inhibitor- reduce LDL 43%-64%