Leqvio Oral Boards- Question 2

Question 1

Obesity

Answer 1

• linked to high triglyceride levels
• high LDL levels
• hypertension, diabetes
• evidence of systemic inflammation

Question 2

Smoking

Answer 2

• Bad
• damages lining of blood vessels
• increases plaque build up, which can increase BP

Question 3

Lack of Physical Activity

Answer 3

• important in general

- for ASCVD, lack of exercise can lead to weight gain and high cholesterol

Question 4

Unhealthy diet

Answer 4

• diets high in trans and saturated fats

- ultra processed diets that are largely consumed

Question 5

hypercholesterolemia

Answer 5

• at risk when LDL-C levels are at 160 or higher.

Question 6

hypertension

Answer 6

-high BP that is greater than 140/90

Question 7

type 2 diabetes

Answer 7

• insulin resistance can lead to high blood sugar

- contributes to high LDL-C and low HDL levels

Question 8

Age

Answer 8

• as you age, your chol levels naturally increase because hepatic clearance of LDL-C becomes less efficient
• men 45 and above and women 55 and above more at risk

Question 9

Family history

Answer 9

• patients who have family that had CV events young or presence of ASCVD early.
• men before 55, women before 65