Leptospirose Flashcards

1
Q

Leptospira interrogans Sorotipo:

A

Icterohemorrhagiea e Copenhageni

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2
Q

Reservatórios:

A

Animais domésticos e selvagens
Homem

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3
Q

Leptospirose clínica 3 fases:

A

Infecção assintomática
Infecção anictérica
Infecção ictérica (S. de Weil)

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4
Q

Infecção anictérica:

A
  • Fase precoce: 80 - 90% das manifestações
  • Fase tardia (imune)
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5
Q

Fase precoce – LEPTOSPIRÊMICA

A
  • Febre
  • Cefaleia
  • Anorexia
  • Mialgia (lombar e panturrilhas)
  • Artralgia
  • Náuseas
  • Vômitos
  • Diarreia
  • Sufusão conjunitival
  • Hepatoesplenomegalias
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6
Q

Fase tardia – IMUNE

A
  • Recrudescência da febre
  • Pneumonite (tosse e hemoptise)
  • Uveíte (uni ou bilateral)
  • Exantema e linfonodopatias
  • Meningite asséptica
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7
Q

Sangue(3) =

A
  • Fígado
  • Rins
  • Coração
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8
Q

Fígado =

A

lise ou lesão hepatocelular

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9
Q

Rins =

A
  • nefrite intersticial
  • necrose tubular
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10
Q

Quadro monofásico - S. Weil

A
  • Persistência da febre
  • Icterícia rubínica
  • IRA não oligúrica (hipocalêmica)
  • Hemorragias (IRpA e hemop=se)
  • Miocardite (hipotensão e arritmias)
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11
Q

Hemograma:

A

anemia, leucocitose e trombocitopenia

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12
Q

EQU:

A
  • Uréia
  • creatinina elevadas
  • Na
  • K
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13
Q

Diagnóstico

A
  • Imunofluorescência
  • Hemocultura
  • Urina
  • Sorologia IgM
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14
Q

TRATAMENTO:

A
  • Hidratação e sintomá=cos
  • Diálise e medidas de suporte
  • ATB: (ideal até o 5o dia)
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15
Q

ATB: (ideal até o 5o dia):

A
  • Amoxicilina
  • Eritromicina
  • Ampicilina
  • Cepriaxona
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