Lecturio 3 Development of spinal cord and brainstem Flashcards
Proliferation of neuroepithelial cells
The region closet to the neural canal is called ____
Ventricular zone
Proliferation of neuroepithelial cells
What is the ventricular zone? What does it contain?
The region closest to the neural canal that contains neuroepithelial cells that are actively dividing
Proliferation of neuroepithelial cells
Neuroepithelial cells migrate into ___ and ____
Intermediate zone and marginal zone
Proliferation of neuroepithelial cells
superficial to the marginal zone is (1) ____
sclerotomal mesenchyme
Proliferation of neuroepithelial cells
superficial to the marginal zone is sclerotomal mesenchyme that will become ___
meninges
Proliferation of neuroepithelial cells
In the spinal cord, the neural canal will become ____
The central canal
Proliferation of neuroepithelial cells
In the spinal cord, the neural canal will become The central canal
→ It is lined by _____
Ependymal cells derived from the neural tube
Proliferation of neuroepithelial cells
→ IDENTIFY
Division of Sensory and Motor Neurons
Neuroepithelial cells take on different roles depending upon their position relative to a dividing line which is called ___
sulcus limitans
Division of Sensory and Motor Neurons
Cells posterior to the sulcus limitans are in ____
the alar plate
Division of Sensory and Motor Neurons
Cells posterior to the sulcus limitans are in the alar plate and become ___
sensory cells and interneurons
Division of Sensory and Motor Neurons
Cells anterior to the sulcus limitans are in ____
the basal plate
Division of Sensory and Motor Neurons
Cells anterior to the sulcus limitans are in the basal plate and become ___
motor neurons
Division of Sensory and Motor Neurons
The neural tube is closed by a (1)____ posteriorly and (2)____ anteriorly
- Roof plate
- Floor plate
Division of Sensory and Motor Neurons
→ Identify (left side)
Division of Sensory and Motor Neurons
→ Identify (right side)
Division of Sensory and Motor Neurons
____ in the anterior horn extend axons to the myotome to innervate skeletal muscles
Motor neurons
Division of Sensory and Motor Neurons
____ in the anterior horn extend axons to the myotome to innervate skeletal muscles
Motor neurons
Division of Sensory and Motor Neurons
Motor neurons in ___ extend axons to the myotome to innervate skeletal muscles
the anterior horn
Division of Sensory and Motor Neurons
___ from posterior root ganglia extend axons to the dermatome and into the posterior horn of spinal cord
Sensory axons
Division of Sensory and Motor Neurons
Sensory axons from posterior root ganglia extend axons to ___ and into the posterior horn of spinal cord
the dermatome
Division of Sensory and Motor Neurons
____ in the posterior horn extend axons superiorly to other regions of the central nervous system.
Sensory cells
Division of Sensory and Motor Neurons
___ in the posterior horn extend to motor neurons in the anterior horn
Interneurons
Division of Sensory and Motor Neurons
Interneurons in the posterior horn extend to ____ in the anterior horn
motor neurons
Division of Sensory and Motor Neurons
→ identify
Sensory and Motor Neurons in the Medulla
The brainstem resembles ____
The spinal cord
Sensory and Motor Neurons in the Medulla
Basal plate will form ____
motor nuclei
Sensory and Motor Neurons in the Medulla
Alar plate will form ____
sensory nuclei
Sensory and Motor Neurons in the Medulla
The basal plate and alar plate are separated by ____
the sulcus limitans
Sensory and Motor Neurons in the Medulla
The caudal medulla resembles ___ (structure?)
The spinal cord
Sensory and Motor Neurons in the Medulla
The caudal medulla resembles The spinal cord with (1)____ developing on its dorsal side and (2)____ on the ventral side
- Sensory nuclei
- Motor nuclei
Sensory and Motor Neurons in the Medulla
→ Identify
≈
The cranial medulla has an expanded roof plate covering ____
4th ventricle
Sensory and Motor Neurons in the Medulla
The cranial medulla has an ___ covering the 4th ventricle
expanded roof plate
Sensory and Motor Neurons in the Medulla
→ identify
Sensory and Motor Neurons in the Medulla
→ Identify
Development of the pons
The pons is connected to ____ posteriorly
The cerebellum
Development of the pons
The pons is connected to The cerebellum posteriorly
→ ___ migrate from the alar plate to a position in the ventral pons
The pontine nuclei
Development of the pons
The pons is connected to The cerebellum posteriorly
→ The pontine nuclei migrate from ____ to a position in the ventral pons
the alar plate
Development of the pons
The pons is connected to The cerebellum posteriorly
→ The pontine nuclei migrate from the alar plate to a position in ____
the ventral pons
Development of the pons
The cerebellum
Development of the cerebellum
The cerebellum develops as a massive expansion off the (1)____, dorsal to (2) ____
- The alar plate
- The pons
Development of the Cerebellum
→ Identify
Development of the Midbrain
The alar plate in the midbrain creates ____ in its original position
Sensory nuclei
Development of the Midbrain
The alar plate in the midbrain creates Sensory in its original position
→ But also give rise to the ___
colliculi (visual and sensory processing)
Development of the Midbrain
→ Identify
Development of the Midbrain
Identify
Development of the Midbrain
The basal. plate also gives rise to ____ in its original position
Motor nuclei
Development of the Midbrain
The basal. plate also gives rise to Motor nuclei in its original position
→ gives rise to ___
Other motor nuclei in the ventral midbrain
Development of the Midbrain
identify
Development of the Thalamus
In the diencephalic region, the alar plate give rise to ___ 93)
- the epithalamus
- pineal gland
- multitude of thalamic nuclei
Development of the Thalamus
In the diencephalic region, the alar plate give rise to
- the epithalamus
- pineal gland
- multitude of thalamic nuclei
→ these nuclei re-route sensory input from ___ to ____
the head, neck and body to various regions of cerebral cortex
Development of the Thalamus
The basal plate gives rise to ____
Hypothalamic nuclei, which control the body’s basic drive and autonomic activities
Development of cerebral cortex
How many embryonic origins does the pituitary gland have?
2
Development of cerebral cortex
→ Identify
Development of cerebral cortex
(1)____ extends inferiorly from the diencephalon and meets an extension of epithelium from the early oral cavity which is (2)-__
- The infundibulum
- Rathke’s pounch
Development of cerebral cortex
→ Identify
Development of cerebral cortex
Rathke’s pouch then detaches from (1)____ and closely associates with (2)___
- The oral cavity
- the infundibulum
Development of cerebral cortex
_____ comes from the Rathke’s pouch
The anterior lobe of the pituitary gland
Development of cerebral cortex
The anterior lobe of the pituitary gland comes from____
the Rathke’s pouch
Development of cerebral cortex
____ arise from the diencephalon and hypothalamic region
The posterior lobe and infundibulum of the pituitary gland
Development of cerebral cortex
The posterior lobe and infundibulum of the pituitary gland arise from ____ and ____
the diencephalon and hypothalamic region
Development of cerebral cortex
Identify
Development of cranial nerves
Any sensory activity of a cranial nerve will be linked to ____ in the dorsal portion of the brainstem
A sensory nucleus
Development of cranial nerves
The cranial nerves that are from the brainstem and spinal cord are linked to the sensory and motor nucleiin its dorsal and ventral regions
→ Any motor activity of a cranial nerve will originate in ____
ganglia in the ventral portion of the brainstem
Development of cranial nerves
Sensory ganglia associated with ___ develop from neural crest cells
CN V, VII, IX & X
Development of cranial nerves
The cranial nerves that are from the brainstem and spinal cord are linked ____ and ___ in its dorsal and ventral regions
to the sensory and motor nuclei
Development of cranial nerves
→ Identify
Development of cranial nerves
→ Identify
Ascent of spinal cord
During early development, around ____ (week?), the spinal cord extends along the vertebral column
week 8
Ascent of spinal cord
The cord does elongate at different rate as the rest of the body
→ Its inferior end “ascends”
→ Reaching _____ vertebral level at birth and ____ level at adult
- L3
- L1
Ascent of spinal cord
The spinal nerve roots that exit below that level are stretched and created a structure called ___
The caudal equina
Ascent of spinal cord
The tapered end of the spinal cord which is called (1)____ remains tethered to the coccygeal vertebrae by a connective tissue thread which is called (2)____
- Conus medullaris
- Filum terminale
Ascent of spinal cord
→ Identify
Ascent of spinal cord
→ Identify
Ascent of spinal cord
→ Identify
Ascent of spinal cord
→ Identify