Development of arteries Flashcards
What is Vasculogenesis
•: fusion of angioblasts (FGF and VEGF growthfactors and their receptors)
What is Angiogenesis?
new vessels develop from buds of the existingvessels.
Angiogenesis
→ identify
Circulating blood cells come from ___ within early vessels
hematopoietic cell clusters
Hematopoietic Cell Clusters
Blood formation will later move to_____ (3)
liver, spleen, thymus, and eventually to bone marrow
Identify
Hematopoietic cell cluster
Major Embryonic Arteries
___ supplies the yolk sac
Vitelline artery
Major Embryonic Arteries
The role of Umbilical arteries
take deoxygenated blood from the fetus to the placenta
Major Embryonic Arteries
The role of Umbilical veins
take oxygenated blood from the placenta to the fetus
Major Embryonic Arteries
____ fuse into a single dorsal aorta developing various segmental branches
The right and left dorsal aortae
Major Embryonic Arteries
The right and left dorsal aortae fuse into a single dorsal aorta developing ___
various segmental branches
Aortic Arches and Large Arteries
Only ____ on each side leading to a right and left dorsal aorta
one aortic arch
Aortic Arches and Large Arteries
→ identify
Aortic Arches and Large Arteries
Only one aortic arch on each side leading to____ and ___
a right and left dorsal aorta
Aortic Arches and Large Arteries
Additional arches form until there are _____
1st, 2nd 3rd, 4th, and 6th arches;
Aortic Arches and Large Arteries
gut tube is (1)____ (anterior/posterior) to developing heart but passes (2)___(anterior/posterior) to fused dorsal aorta
- posterior
- anterior
Aortic Arches and Large Arteries
gut tube is posterior to developing heart but passes anterior to ____
fused dorsal aorta
Aortic Arches and Large Arteries
gut tube is posterior to ____ but passes anterior to fused dorsal aorta
developing heart
First and Second Aortic Arches
Forming mature circulation, parts of this system close and separate from their neighbors
1st arch disappears, leaving small proximal portion that contributes to ____
maxillary artery
First and Second Aortic Arches
Forming mature circulation, parts of this system close and separate from their neighbors
2nd arch also disappears, leaving small ___
stapedial artery
Forming mature circulation, parts of this system close and separate from their neighbors
___ also disappears, leaving small stapedial artery
2nd arch
Forming mature circulation, parts of this system close and separate from their neighbors
___ disappears, leaving small proximal portion that contributes to maxillary artery
1st arch
3rd and 4th Aortic Arches
3rd arch becoming _____ and _____ ; remains attached to dorsal aorta cranial to it
common and internal carotid artery
3rd and 4th Aortic Arches
3rd arch becoming common and internal carotid artery; remains attached to ____ cranial to it
dorsal aorta
___ becoming common and internal carotid artery; remains attached to dorsal aorta cranial to it
3rd arch
3rd and 4th Aortic Arches
Section of ____ between 3rd and 4th arch rescinds, separating two arches from each other
dorsal aortae
3rd and 4th Aortic Arches
Leaves 4th arch connected to more caudal regions of dorsal aorta on both sides; will contribute to ____ and ____
aortic arch (left) and subclavian artery (right)
Leaves ____ connected to more caudal regions of dorsal aorta on both sides; will contribute to aortic arch (left) and subclavian artery (right)
4th arch
Leaves 4th arch connected to more caudal regions of ____ on both sides; will contribute to aortic arch (left) and subclavian artery (right)
dorsal aorta
Blood Supply - 6th Aortic Arch
Relationship between the aortic arches and the developing gut tube
→ Aortic arches are within pharyngeal arches and run ____
between adjacent pharyngeal pouches
Blood Supply - 6th Aortic Arch
Relationship between the aortic arches and the developing gut tube
→ Aortic arches are within pharyngeal arches and run ____
between adjacent pharyngeal pouches
Blood Supply - 6th Aortic Arch
Relationship between the aortic arches and the developing gut tube
→ Aortic arches are within ____
pharyngeal arches
Blood Supply - 6th Aortic Arch
Relationship between the aortic arches and the developing gut tube
→ 6th aortic arches connect to ____
aortic sac, dorsal aorta, AND developing lung buds
→ becoming pulmonary arteries
Blood Supply - 6th Aortic Arch
Relationship between the aortic arches and the developing gut tube
→ 6th aortic arches connect to aortic sac, dorsal aorta, AND developing lung buds; becoming ____
pulmonary arteries
As aortic arches develop, heart’s outflow tracts partitions into ___ and ___
→ Aorta propels blood into derivatives of 3rd and 4th arches
aorta and pulmonary trunk
Morphologic Changes of Aortic Arches
As aortic arches develop, heart’s outflow tracts partitions into ___ and ___
aorta and pulmonary trunk
Morphologic Changes of Aortic Arches
As aortic arches develop, heart’s outflow tracts partitions into aorta and pulmonary trunk
- Aorta propels blood into derivatives of __and _
- Pulmonary trunk propels blood into pulmonary arteries, derivatives of ___
- 3rd and 4th arches
- 6th arches
Morphologic Changes of Aortic Arches
On the right, connection between 6th arch and dorsal aorta remains as _____
ductus arteriosus
Morphologic Changes of Aortic Arches
On the right, connection between ____ and ____ remains as ductus arteriosus
6th arch and dorsal aorta
Morphologic Changes of Aortic Arches
Simultaneously, 7th intersegmental artery enlarges and extends into ____
developing upper limb
Morphologic Changes of Aortic Arches
Simultaneously, ____ enlarges and extends into developing upper limb
7th intersegmental artery
Morphologic Changes of Aortic Arches
Right dorsal aorta rescinds between ____ and ____
7th intersegmental artery and fused dorsal aorta
Morphologic Changes of Aortic Arches
____ rescinds between 7th intersegmental artery and fused dorsal aorta
Right dorsal aorta
First and Second Aortic Arches
→ identify
3rd and 4th Aortic Arches
→ identify
6th Aortic Arch
→ identify
6th Aortic Arch
→ identify
Morphologic Changes of Aortic Arches
Course of the Recurrent Laryngeal Nerves
The recurrent laryngeal nerves originally curve around the _____.
6th aortic arches
•The coronary arteries develop from _____
the proepicardial body
