Lectures 1-4 Flashcards
1
Q
Definition of EBM:
A
- medicine combining the best current research evidence with clinical expertise and patient values.
2
Q
The five outcomes of disease:
A
- death
- disease
- discomfort
- disability
- dissatisfaction
3
Q
Prevalence =
A
(total #sick)/(total population)
- how many people are sick
- a single time point
- Prevalence can be used to estimate the likelihood of a diagnosis before any “tests”
4
Q
Cumulative incidence:
A
(new cases)/(total population at risk at study start)
- how many people are getting sick (NEW CASES)
- incidence is a rate, it happens over a time interval
5
Q
Incidence density =
A
- the incidence rate in a dynamic, changing population in which people are under study and at risk for varying periods of time.
- “person-years” or “person-days”
6
Q
Incidence equation in steady state:
A
prevalence / duration
7
Q
Duration equation in steady state:
A
prevalence / incidence
8
Q
Prevalence equation in steady state:
A
(incidence) X (average duration)
9
Q
Apparent incidence depends on:
A
- intensity of effort to identify cases, not just the true underlying incidence.
10
Q
Epidemic:
A
- an increase in incidence of a disease in a community or region.
- Outbreak is sometimes used to mean a small epidemic in a limited location.
- An epidemic curve is a plot of the distribution of cases over time.
11
Q
Pandemic:
A
- an epidemic that crosses many international boundaries.
12
Q
Endemic:
A
- the constant presence of a disease or infectious agent within a given geographic area or population group.
13
Q
Random samples:
A
- Every person has an equal probability of being sampled
14
Q
Probability sample:
A
- Every person has a known (but not necessarily equal) probability of being selected.
- Can weight the sample towards some low-frequency groups of interest.
15
Q
“grab” samples:
A
- convenient
- susceptible to bias
16
Q
alpha =
A
- the probability you’ll make a false hit.
- Arbitrarily, p = 0.05
- false hit = type 1 error
- 5% of the time, we’ll make an error