LECTURE XII Flashcards
these are agents that induce congenital malformations
teratogens
this is the result of non therapeutic drugs causing cognitive problems, behavioral problems, facial features, and increased likelihood of miscarriage and prematurity
fetal alcohol syndrome caused by alcohol
this anti seizure drug causes this syndrome with the newborn displaying cleft lip or cleft palate, susceptibility fo congenital heart disease, delayed growth with cognitive defects
fetal hydantoin syndrome
this infectious disease is due to the virus infecting the embryo with the baby having cardiac defects, cataracts, deafness, microcephaly, chorioretinitis, mental retardation, glaucoma
rubella virus or German measles
an abnormality inherited and present at birth?
congenital infection
often referred to period from 7 mo of gestation to 1 mo after birth
perinatal
this infectious disease occurs to the embryo when the mother gets infected during the embryonic period, the baby shows skin abnormalities, muscle atrophy, mental retardation
chicken pox, varicella zoster virus
this is an infectious disease when an intracellular parasite causes infection from cats, the mother gets it from eating infected food which then gets to the fetus, this causes intracerebral calcification, chorioretinitis, microphthalmia
toxoplasma gondii
this is a stage of syphillis that affects the mother during the fetal period and then the fetus gets infected?
primary syphilis
this stage of syphilis in which this can lead to congenital syphilis in the newborn without malformation?
secondary or tertiary syphilis
this disease is due to nonteratogenic infections that can lead to congenital infection and so this one can have affect the baby via mom during the embryonic or fetal period, abortion and stillbirth can happen, no malformations associated, this disease infects and lyses erythroblasts, no vaccines
erythema infectiosum
this disease is due to nonteratogenic infections that can lead to congenital infection, primary infection in women during fetal period can lead to fetal infection, this is acquired from contaminated water, headache, fever, myalgia, rash presentation
leptospira interrogans
what is the outcome of exposure to teratogens during the zygotic period?
death of embryo and spontaneous abortion
what is the outcome of exposure to teratogens during the embryonic period?
major congenital anomalies
what is the outcome of exposure to teratogens during the fetal period?
functional defects and minor anomalies