HISTORY OF MODERN MEDICAL GENETICS Flashcards
LECTURE 1 CHECK ON LEARNING
On the Origin of Species
Darwin
Nature of Inheritance
Gregor Mendel
Classical Experimental Genetics
Thomas Hunt Morgan
Discovered that genes are mobile, like Transposons
Barbara McClintock
Structural conformation that DNA contained the genetic information not the proteins for the basis of genetics
James Watson, Francis Crick, Rosalind Franklin
DNA analytic methods
Sir Ed Southern
Polymerase Chain Reaction
Kary Mullis
using EST sequencing (cloned fragments of cDNA) to accelerate finding genes and charactering function
Human genome project by Craig Ventor
Director of NIH Human Genome Project Announced
Francis Collins
controlled gene knockdown
Morpholino Oligonucleotides
Cas9 system used for gene knockout
Yoshizumi Ishino- CRISPR