HISTORY OF MODERN MEDICAL GENETICS Flashcards

LECTURE 1 CHECK ON LEARNING

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1
Q

On the Origin of Species

A

Darwin

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2
Q

Nature of Inheritance

A

Gregor Mendel

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3
Q

Classical Experimental Genetics

A

Thomas Hunt Morgan

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4
Q

Discovered that genes are mobile, like Transposons

A

Barbara McClintock

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5
Q

Structural conformation that DNA contained the genetic information not the proteins for the basis of genetics

A

James Watson, Francis Crick, Rosalind Franklin

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6
Q

DNA analytic methods

A

Sir Ed Southern

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7
Q

Polymerase Chain Reaction

A

Kary Mullis

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8
Q

using EST sequencing (cloned fragments of cDNA) to accelerate finding genes and charactering function

A

Human genome project by Craig Ventor

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9
Q

Director of NIH Human Genome Project Announced

A

Francis Collins

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10
Q

controlled gene knockdown

A

Morpholino Oligonucleotides

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11
Q

Cas9 system used for gene knockout

A

Yoshizumi Ishino- CRISPR

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