Lecture: Neurotransmitters Flashcards

1
Q

amino acid neurotransmitter(s)

A

Glutamate
Aspartate
Glycine
GABA

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2
Q

What are the two categories of monoamines?

A

Catecholamines
Indolamines

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3
Q

Monoamine catecholamine neurotransmitter(s)

A

Dopamine
Epinephrine
Norepinephrine

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4
Q

Monoamine Indolamine neurotransmitter(s)

A

Serotonin

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5
Q

Soluble gas neurotransmitters

A

Nitric oxide
Carbon monoxide

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6
Q

Acetylcholine neurotransmitter(s)

A

Acetylcholine

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7
Q

Which neurotransmitter is its own class?

A

Acetylcholine

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8
Q

Neuropeptide neurotransmitter(s)

A

Endorphins

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9
Q

Most common excitatory neurotransmitter in the bran

A

Glutamate

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10
Q

Predominant ionotropic Glutamate receptor

A

NMDA

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11
Q

What neurotransmitter is termed the “on switch” for the brain?

A

Glutamate

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12
Q

Glutamate ionotropic receptor(s)

A

AMPA
NMDA
Kainate

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13
Q

Glutamate metabotropic receptor(s)

A

mGluRs

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14
Q

Neural injury that causes excess release of glutamate, killing neurons

A

Excitotoxicity

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15
Q

What results in excitotoxicity

A

Stroke
Head Trauma

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16
Q

Most common inhibitory neurotransmitter in the brain

A

GABA

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17
Q

Ionotropic GABA receptor(s)

A

GABA subscript A

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18
Q

GABA agonists are potent ______

A

Tranquilizers

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19
Q

GABA agonists:

A

Valium
Barbiturates
Ethanol
Neurosteroids
Benzodiazepines

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20
Q

What might benzodiazepines be used for?

A

Stop seizures
Antidepressants

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21
Q

What might barbiturate be used for?

A

Sleeping pills
Anesthesia

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22
Q

What is the neurotransmitter in alcohol?

A

Ethanol

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23
Q

Most common inhibitory neurotransmitter in the spinal cord

24
Q

What is the neurotransmitter for adrenaline?

A

Epinephrine

25
What does dopamine facilitate?
Addiction Learning Schizophrenia Motor Control
26
Dopamine pathway(s)
Mesolimbocortical Mesotriatal
27
Where does the mesotriatal pathway go for dopamine?
Substantia nigra to striatum (Caudate and putamen)
28
Where does the mesolibocorotical pathway go for dopamine?
Ventral tegmental area to nucleus accumbens, cortex, and hippocampus
29
What is Norepinephrine vital for?
Mood Arousal Sexual Behavior
30
Where does the norepinephrine pathway travel?
Locus Coreleus to hippocampus, basal ganglia, and cortex Lateral Tegmental area
31
What is serotonin vital for?
Sleep Sexual Behavior Anxiety
32
What neurotransmitter is responsible for anxiety and panic attacks?
Serotonin
33
What structures are vital to the serotonin pathway?
Hippocampus (under the surface) and Raphe Nuclei
34
What is the serotonin pathway?
Mesencephalic serotonergic cells project to thalamus, hypothalamus, basal ganglia, and cortex
35
What state of matter are the nitric oxide and carbon monoxide neurotransmitters?
Gasses
36
Nitric oxide is produced in _____ of the _____ cell and diffuses _____
Dendrites Postsynaptic Instantly
37
Gas neurotransmitters are diffused to ____ cells
Nearby
38
Gas neurotransmitters _____ neighboring neurons
Synchronize
39
Can gasses be stores in vesicles?
No
40
Acetylcholine receptor(s)
Nicotinic Muscarinic
41
Agonists for acetylcholine
Nicotine Muscarine
42
What is Curare good for?
Helps with suffocation from seizures Relaxes muscles and paralyzes patients
43
Most nicotinic ACh receptors are:
Ionotropic Excitatory Peripheral
44
Most muscarinic ACh receptors are:
Metabotropic Excitatory or inhibitory CNS
45
_____ use nicotinic ACh receptors
muslces
46
Is glutamate excitatory or inhibitory?
Excitatory
47
Is asparate excitatory or inhibitory
Excitatory
48
Is glycine excitatory or inhibitory?
Inhibitory
49
Is GABA excitatory or inhibitory
Inhibitory
50
Is dopamine excitatory or inhibitory?
Neither
51
Is epinephrine excitatory or inhibitory?
Excitatory
52
Is norepinephrine excitatory or inhibitory?
Excitatory
53
Is serotonin excitatory or inhibitory?
Inhibitory
54
Is nitric oxide excitatory or inhibitory?
Both
55
Is carbon monoxide excitatory or inhibitory?
inhibitory
56
Is acetylcholine excitatory or inhibitory?
Excitatory
57
Are endorphins excitatory or inhibitory?
Inhibitory