Lecture: Neurolocalization Flashcards

1
Q

Brain and Cranial nerves

A
  • Forebrain
    • Cerebrum: I
    • Diencephalon: II
  • Cerebellum
  • Brainstem
    • Midbrain: III-IV
    • Pons: V
    • Medulla oblongata: VI-XII
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2
Q

Forebrain

A

INHIBITORY

CS

  • Seizures
  • Circling
  • Compulsion
  • Behavior changes
    • inappropriate
    • getting stuck in corners
  • Blindness (amaurosis)
  • Postural reaction deficits
  • Gaint should be normal
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3
Q

Amaurosis

A

Non-ocular blindness

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4
Q

Horner’s Syndrome

A

Loss of sympathetic innervation to eye

CS

  • Ptosis
  • Prolapsed 3rd eyelid
  • Miosis
  • Enopthalmos

*Horses with Horner’s are hyperthermic and sweat unilaterally

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5
Q

Cerebellum Signs

A
  • Intention tremors
  • Head tilt
  • Nystagmus
  • Loss of menace
  • Truncal sway
  • Ataxia
  • Hypermetria
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6
Q

NOT Cerebellar signs

A
  • Paresis
  • Behavior changes
  • CP deficits
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7
Q

Cerebellar Ataxia

A
  • Hypermetria
  • ‘spastic’
  • NO PARESIS
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8
Q

Brainstem Signs

A
  • Decreased mentation (ARAS)
    • reticular activating system runs through brainstem
    • obtunded to stuporous to comatose
  • CN deficits
  • Usually some CN VIII involvement
    • Check for physiologic nystagmus
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9
Q

Brainstem: Gait

A
  • Vestibular or proprioceptive ataxia
    • if ambulatory
    • may seem cerebellar depending on lesion
  • Tetraparesis (will always be seen w/ brainstem lesions)
  • Proprioceptive deficits
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10
Q

Neurolocalization: Spine

A
  • C1-C5: All 4 limbs (equally affected)
  • C6-T2: All 4 limbs (thoracic [LMN] different to pelvic [UMN] limbs)
  • T3-L3: Only pelvic limbs affected
  • L4-S3: Only pelvic limbs affected (LMN)
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11
Q

Segmental Reflexes

A
  • Can sever spinal cord cranial or caudal to the intumescense and reflex will still be intact
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12
Q

Withdrawel reflex is NOT

A

Conscious

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13
Q

Extended, difficult to flex limb

A

Implies UMN lesion

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14
Q

Flaccid, unable to support any weight

A
  • Implies LMN involvement
  • Consider spinal shock
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15
Q

Localization: C1-C5

A
  • +/- ambulatory
    • knuckling, stumbling, ‘face-planting’
  • Tetraparesis
  • Ataxia
    • TL signs more subtle than PL
  • Reflexes: N to inc on all limbs
  • +/- muscle fasciculations
  • +/- Pain
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16
Q

Localization: C6-T2

A
  • +/- ambulatory
    • knuckling, stumbling, ‘face-planting’
    • ‘two-engine’ gait
  • Tetraparesis
  • Ataxia
  • Reflexes
    • TL: N to dec
    • PL: N to inc
  • +/- muscle fasciculations
  • +/- Pain
17
Q

Localization: T3-L3

Classic Dachshund

A
  • +/- ambulatory
  • Paraparesis
    • increased PL tone
  • PL ataxia
  • +/- Kyphosis
  • Reflexes:
    • TL: N
    • PL: N to inc
    • +/- Panniculus cut-off
  • +/- pain
    • usually painful
18
Q

Kyphosis

A

hunched back

19
Q

Spinal shock

A
  • Not prognostic
  • Localization T3-L3
  • Physiologic or anatomic transection of spinal cord
    • causes temporary loss or depression in muscle tone and spinal reflex below injury
  • associated with acute injury
  • Patellars return within hours in dogs
  • Withdrawel can take days to return
20
Q

Schiff-Sherrington posture

A
  • Not prognostic
  • Localization to T3-L3
  • Extensor hypertonia of TLs
  • due to loss of ascending inhibition
  • Associated with severe TL lesions
    • plegia +/- pain perception
  • Distinguish from decerebrate and decerebellate postures
    • mentation, CNs
21
Q

Localization: L4-S3

A
  • +/- Ambulatory
  • PL Ataxia
  • +/- pain
  • Paraparesis
    • Decreased PL muscle tone
  • Reflexes
    • TL: N
    • PL: dec to absent
    • +/- panniculus to cut-off
    • Anal tone?
    • Perineal reflex?
    • Tain tone?
    • Tail sensation?
22
Q

Localization: LMN

A
  • +/- ambulatory
  • NO ATAXIA
  • NO PAIN
  • +/- CN weakness
    • gag, facial
  • Paresis
    • decreased muscle tone all over
  • Reflexes
    • dec to absent
    • +/- panniculus affect
  • Exercise intolerance
    • hallmark for myasthenia gravis
23
Q

DDX

Chondrodystrophoid

A
  • IVDD
24
Q

DDX

Acute non-progressive

A
  • Vascular
  • Trauma
  • IVDD
25
Q

DDX

Acute Progressive

A
  • Trauma
  • IVDD
  • Neoplasia
  • Inflammatory
  • Infectious
26
Q

DDX

Chronic progressive

A
  • Neoplasia
  • Degenerative
  • IVDD
  • Inflammatory
  • Infectious
27
Q

There are no nerve endings within

A

Spinal cord

28
Q

Painful spinal lesions

A
  • IVDD
  • Meningitis/meningomyelitis
  • Diskospondylitis
  • Fracture/luxation
  • Neoplasia (bone)