Lecture - limbic system Flashcards
Broca
-Broca: ring of cortical areas (cingulate gyrus and hippocampus) in close connection with olfactory system
james papez
-added mammillary bodies and thalamus to Brocas map
Mclean
-amygdala, PFC, hypothalamus
Limbic system
- cingulate gyrus
- thalamus
- hypothalaus
- amygdala
- hippocampus
- OFC
- mammillary bodies
stress
- loss of control on its environment (uncertainty, not able to predict or influence its relevant environment
- acute
- chronic
internal vs external behavior
- internal: physiological response
- external: behavioral
- > one wants to maintain homeostasis internal and external environment
physiogical responses to stress
- autonomic NS (sympathetic system)
- > activation adrenals (medulla) -> adrenaline (fight flight)
- > 2 to 20 sec
- endocrine system
- over 20 secs, days, weeks, months
- Hypothalamus Pituitary Adrenal cortex (HPA - axis)
- > production of cortisol (produced in cortex of adrenals)
ANS (2)
- sympathetic -> prepare for action
- parasympathetic -> prepare for rest
Amygdala input/output
- basal lateral amygdala -> major input
- central -> major output
..
- amygdala -> lateral hypothalamus -> spinal cord -> adrenaline
- amygdala paraventricular nucleus ->
fear vs anxiety
Fear. phasic response to explicit aversive cues / stimuli
anxiety: tonic response to diffuse aversive stimuli -> associated with approaching potentially! dangerous situations
anxiety brain structures
- medial PFC
- > cingulate cortex
- > ventral hippocampus
- > amygdala (BLA) -> basal lateral
fear brain structures
..
endocrine system
- over 20 secs, days, weeks, months
- Hypothalamus Pituitary Adrenal cortex (HPA - axis)
- > production of cortisol (produced in cortex of adrenals)
Acute effects cortisol
- suppression of HPA axis ( negative feedback)
- mobilization of energy
- suppression of immunity (anti-inflammatory)
- behavioral inhibition/attention (medial PFC)
- motivation (orbitofrontal cortex, n. accumbens)
- memory (hippocampus)
Klüver-bucy syndrome
-fear/anxiety and aggression decrease
-memory deficits
Amygdala stimulation
-plase nor
coping
-try to influence/control its environment in response towards the stressor
hippocampus function
- storage of LTM
- declarative
cued fear conditioning
…
context fear conditioning
-contextual stiumulus
-> ventral Hippocampus
….
amygdala -> between emotion and memory
- amygdala mediates
- procedural memory
- emotio…
