Lecture exam #2 Flashcards
Epidermis
Stratified squamous epithelium
Avascular
Contains free nerve endings
Skin consists of 2 layers
Epidermis and Dermis
Dermis
Connective tissue
Contains blood vessels and nerves
Stratum basale = stratum germinattivum
- Deepest layer
- -Mostly keratinocyte stem cells
- SINGLE layer of columnar shaped cells
Actively mitotic
Stratum spinosum
second layer from bottom
Several layers
Looks prickly
Contains: keratinocytes, dendritic cells, melanin, pre-keratin filaments
Stratum Granulosum (3rd layer from bottom)
Mitosis to make cells tough & protective
Granules:: keratohyaline & lamellated
HOLDS DARKER STAIN
Stratum lucidum
Only thick skin (4th layer up)
2-3 rows of clear, flat, dead keratinocytes
Stratum corneum (top layer )
Cells are dead
Protects; physical barrier
2 main cell types in dermis
Fibroblasts, macrophages &
sometimes mast cells & WBC
3 sensory structures of dermis
Miessner’s corpuscles - light touch
Pacinian corpuscles- deep pressure & vibration
Free nerve endings- respond to pain
4 accessory organs of skin
- Sweat glands
a) eccrine b) apocrine both merocrine glands - Sebaceous (oil) glands
- nails
- Hair
PERICHONDRIUM (dense Ct)
Surrounds cartilage
Provides nutrient supply
Provides structural support
Skeletal cartilages
Hyaline
Elastic
Fibrocartilage
Growth of cartilage
Flexible matrix allows for mitosis
2 types of bone growth
Appositional– outward expansion
Interstitial growth– expansion from within
Storage in bones (5)
Minerals (calcium &phosphorus) Growth factors Triglycerides- fat storage Blood cell formation (hematopoiesis) in marrow cavities Hormone production (osteocalcin)
Epiphyses
Ends of bones
Articulate cartilage
Hyaline cartilage covering joints surface
Diaphysis
Shaft- surrounds marrow cavity
Medullary cavity
Filled with marrow.
Yellow=fat Red = infants
Epiphyseal line
Remnant of epiphyseal plate- growth plate
Periosteum
Double layered membrane covering surface of bone
Sharpey’s fibers
Attach periosteum to bone
Endosteum
Membrane covers internal surface and bone.
Contain bone building and bone destroying cells
Red marrow
Hematopoietic tissue
Yellow marrow
Fat in medullary cavities