Lecture 9a: Bioenergetics- cellular respiration Flashcards
Cellular Respiration
the process by which cells generate ATP through a series of redox reaction; electrons are removed from various molecules such as glucose and passed through intermediate electron carriers to a final electron acceptor
Aerobe
organism that grows or metabolizes only in the presence of oxygen (plants and animals)
Anaerobe
an organism that grows only in the absence of oxygen (sulphate-reducing bacteria)
Facultative anaerobe
organism capable of carrying out aerobic respiration but able to switch to fermentation when oxygen is unavailable (E.coli + yeast)
Double-membrane mitochondrion structure
- Outer membrane
- Inner membrane
- Intermembrane space
- Matrix
- Folds (cristae)
Aerobic Respiration involves 4 stages:
- Glycolysis
- formation of acetyl-CoA
- Krebs cycle
- Electron transport chain/chemiosmosis
Glycolysis
- First stage of cellular respiration for all organisms
- Occurs in cytoplasmic fluid
- produces 2 pyruvate, 2 ATP and 2 NADH
Kreb’s Cycle
- 8 steps
- produces citric acid, 2 ATP, 6 NADH, and 2FADH2
Electron Transport Chain
the chain contains 3 (4) large enzymes
i: NADH-Q reductase complex
ii: (succinate-Q reductase complex)
iii: Cytochrome b/c1 reductase complex
iv: Cytochrome c oxidase complex
oxidative phosphorylation
this exergonic process drives the endergonic reaction, in which ATP is produced by phosphorylating ADP
Carbohydrates
Glucose and other sugars. Entering glycolysis
Proteins
amino acids e.g. Alanine- pyruvate
glutamate- ketoglutarate
aspartate- oxaloacetate
Fats
Glycerol and fatty acids
Alcoholic fermentation
yeasts and certain bacteria convert the pyruvate produced by glycolysis to C)2 and ethanol
Lactic acid fermentation
in some fungi and bacteria, lactic acid, rather than alcohol, is produced when NADH from glycolysis is oxidized