Lecture 9- Vision Flashcards
What is sensation?
-How cells of the nervous system detect stimuli in the environment (light, sounds, heat)
-they transduce these signals into a change in membrane potential and neurotransmitter release.
What is perception?
To consciously experience and interpretation of sensation info
Sensory neurons are specialized to detect specific categories of physical events such as:
-Specific molecules
-Physical temperature
-Temperature
-PH
-Electromagnetic radiation
Sensory transduction:
Process by which sensory stimuli are transduce into receptor potentials
Receptor potential:
Graded change in the membrane potentials of a sensory neuron caused by sensory
Sensory neuron:
Specialized neuron detecting specific physical events
Opsins are receptor proteins sensitive to light, they are inhibitory metabotropic receptors,
what are the 4 different opsins to detect light:
-Rhodopsin
-Red cone
-green cone
-Blue cone
Photo receptors:
The sensory neurons responsible for vision by transducing electromagnetic energy of visible light into receptor potentials.
Describe what the Red, blue and green cone opsins individually sensitive to:
And when red and green are too close, they appear:
Red: Sensitive to long wavelengths
Blue: Sensitive to short wavelengths
Green: Sensitive to medium wavelengths
-Yellow
The 3 dimensions of perception of light and colour are:
- Brightness (intensity)
- Saturation (purity)
- Hue (dominant wavelength)
If brightness or saturation is at 0% the image will be:
brightness: black (no impact from saturation or hue)
saturation: middle colour/ no colour (equal contribution from all wavelengths=black and white images)
Protanopia 1% of males:
The absence of red cone opsin, Red cone cells get filled with green opsin.
= cant distinguish green, yellow, red
Deuteranopia 1% of males:
The absence of green cone opsin. Green cone cells get filled with red opsin.
=cant distinguish red, green, yellow
Tritanopia:
Absence of blue cone cells. No compensation, but blue opsin is not too sensitive to light,
= visual acuity is not affected
Achromatopsia:
Colorblindness: mutations in g proteins signalling cascade.
What is the difference from Rod cells and Cone cells
rod cells are sensitive to visible light and cone cells and not very sensitive, but there are 3 so they are each uniquely sensitive to wavelengths.
Describe simply the functions of
-Conjunctiva
-Cornea
-Iris
-Pupil
-Lens
-Retina
-Photoreceptor cells
-Fovea
-Optic disk
-Conjunctiva: mucous membrane lines the eyelid
-Cornea: outer, front layer focuses on incoming light
-Iris: ring of muscle (contraction of this determines size of pupil
-Pupil: determines how much light can enter eye
-Lens: Several transparent layers (allows eye to focus)
-Retina: interior lining of the eye
-Photoreceptor cells: either rod or cone cells
-Fovea: central of eye, little compression of visual info
-Optic Disk: Where optic nerve exits through back of eye (blind spot)
what is foveal vision compared to peripheral vision
Foveal is sensitive to detail and colour, peripheral is sensitive to dim light
Describe cones:
-Found in Fovea
-Sensitive to moderate to high levels of light
-provide info about hue
-excellent acuity
Describe Rods:
-prevalent in peripheral retina
-sensitive to low levels of light
-monochromatic info
-poor acuity
What is saccadic movement and pursuit
Saccadic is rapid jerky shifts of eye, pursuit allows us to maintain image of moving object.
Bipolar cells vs Ganglion cells
bipolar: neurons that relay information form the photoreceptor cells to ganglion cells
ganglion: the only neurons in the retina that sends axons out of the eye, Receive info from bipolar cells and project to the rest of the brain
When photoreceptors are more depolarized:
release more glutamate in the dark than in the light
Off vs On bipolar cells:
OFF bipolar cells: ionotropic glutamate receptors, they are depolarized by glutamate, they are more active in the dark (depolarized)
ON bipolar cells: inhibitory metabotropic glutamate receptors so they are uncommonly inhibited by glutamate, more active in the light
Receptive field:
Involved in visual processing defined as the area of visual space where the presence of light influences the firing rate of that neuron
First, Second and Third cell pathways:
First cell pathway: when the correct wavelength of light is presented in a photoreceptor cells receptive field, hyperpolarizes and becomes less active
Second cell pathway: bipolar cells, light is presented in the receptive field of bipolar cells, depolarizing and releasing more glutamate. Off bipolar cells, thye hyperpolarize and release less glutamate
Third cell pathway: retinal ganglion cells generally integrate information form many on and off bipolar cells.
Simple cells:
In the primary visual cortex are sensitive to lines of light, their receptive field are typically organized in a center surround fashion.
Primary visual cortex:
-neurons have longer receptor field then he retinal ganglion cells
-cell responds better when line is in a particular orientation
-some neurons respond better to vertical lines, and some horizontal lines