Lecture 9 - Regulation of Animal Cell shape Flashcards

1
Q

The cytoskeleton is highly
__________ but still provides
___________

A

The cytoskeleton is highly
dynamic but still provides
stability

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2
Q

What are the three main components that the cytoskeleton is made up of?

A

Intermediate filaments, Microfilaments and Microtubules

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3
Q

Microtubules resist…

A

Compression

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4
Q

What are microtubules composed of?

A

Tublin subunits

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5
Q

Microtubules provide cell…

A

Structure and motility

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6
Q

What is the direction of flagella?

A

“Swimming”

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7
Q

What is the direction of cillia?

A

Side to side

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8
Q

What are microfilaments composed of?

A

A double chain of actin subunits

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9
Q

Microfilaments resist…

A

Tension

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10
Q

Interactions between actin and ______ _______ such as myosin support cell movement

A

Motor proteins

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11
Q

What allows for muscle contraction?

A

Actin-myosin

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12
Q

What are intermediate filaments made of?

A

Keratins (hair), lamins (nucleus) and neurofilamens (neurons)

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13
Q

What do the intermediate filaments help with? (2)

A
  • Maintain cell shape
  • Anchor organelles
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14
Q

T or F

Microtubules are involved in cell
motility (e.g. cilia movement)

A

True

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15
Q

T or F

Microfilaments resist compression

A

False, they resist tension. Microtubules resist compression

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16
Q

T or F

Keratins are an example of
microtubules

A

False, Keratins are an example of intermediate filaments

17
Q

What are the three major types of cell junctions?

A
  • Tight Junctions
  • Desmosomes
  • Gap Junctions
18
Q

What are the roles of tight junctions?

A
  • Hold neighbouring cells tightly
    pressed together
  • Prevents movement of fluid
    across cell layers
19
Q

What are the benefits of gap junctions?

A
  • Ions and small molecules can
    pass from cell to cell
  • Allows rapid cell to cell
    (intercellular) communication
20
Q

How are cells joined together?

A

The extracellular matrix

21
Q

What is the ECM composed of?

A

Material secreted from cells by constitutive exocytosis

22
Q

What are most ECM proteins called?

A

Glycoproteins (protein with
added carbohydrates)

23
Q

What is the most abundant ECM
glycoprotein?

24
Q

Which component of the cytoskeleton resists compression AND is involved in cell motility?

A

Microtubules

25
Which component of the cytoskeleton is involved with contraction of muscle?
Actin-myosin
26
Which component of the cytoskeleton is involved with holding organelles in place?
Microtubules
27
Which component of the cytoskeleton is involved with a flagellum?
Microtubules
28
What are two types of microtubules?
Cilia and flagella
29
Which of the following best describes a cell junction that strongly anchors cells together: A. Tight junction B. Desmosome C. Gap junction D. ECM
Tight junction
30
What are desmosomes?
- Anchoring junction - Provide attachments between sheets of cells e.g. muscle - Connected into the cell by intermediate filaments
31
What is the role of fibronectins (glyoproteins)?
Attaching cells to ECM
32
What is the role of integrins (membrane proteins)?
Connecting the ECM to cytoskeleton.