Lecture 9 - Regulation Flashcards
Describe the absoprtive phase
- excess of Glucose and amino acids is stored
- as glucose in blood increases, PNS is activated
- Physiological changes occur, including bile released to digest lipids and gastro-intestinal system is no longer inhibited by sns
- more insulated secreted by pancrease for glucose uptake in cells (not brain cells)
- insulin move glucose from blood -> cells
What is the principle sources of energy?
glucose and amino acids
What does too much glucose do?
Make blood syrupy, doesnt work, need optimal level (diabetes)
How is food stored short term?
Glucose is stored as glycogen (carb) stored in muscles and liver, to convert later back to glucose (fuel for brain(
how is food intake stored long term?
Fat = tyrigylceride = glycerol (carb) + fatty acids
- stored under skin/ around organs - harmful
What are the environmental cues to satiety
- Clock/ schedules (learned)
- Smells/ sight/ taste
- anticipations of food lowers glucose in blood - low glucose levels make you hungry - Size of meal/ fat content - small portions = nicer, if distracted by others/ tv you eat more
What are body areas give cues to feeding/ satiety?
- Intenstines give sinals to brain via CCK and PYY chemicals
- Liver + panrease (insulin) feedback to hypothalamus
- Adipose tissue growth produces LEPTIN - tells brain to stop eating
How does brain receive info about fullness?
Body parts send signals to
• Lateral hypothalamus (NPY)
• Arcuate nuclueus hypothalamus (Leptin goes here)
- when receiving leptin, this area produces NEUROPEPTIDE Y
What does neuropeptide y do?
Regulates feeding, starting feeding, its under control from Leptin and ventromedial nuclues in hypothalamus
Outline Ventromedal Nucleus
In the hypothalamus, regualted feeding via NPY
When lesioned in a rat, they couldnt stop eating. But it isnt just the VMN that controls eating, its loads of things
Outline how starvation occurs
SNS is activated as glucose levels drop too much in blood, due to:
• Adrenal medulla (adrenaline - feel jittery)
• ADipose tissue (break down fats)
• Pancrease (stops secreting insulin, now secretes glucagon, using glycogen stores from liver and muscles to make energy)
What are the resaons that people over eat?
• Leptin deficiency/ faulty leptin receptors
- Doenst cause obesity tho
• Genetic differences
- Maybe afircan americans passed on very slow metabolisms
• learning from parents/ evolution
- capitalise on high salt/sugar/ fat foods when we can
- learn portions, less excercise, grazing/ snacking
•Serotonin
- can help suppress eating and lose weight
- can help against bulimia, not anorexia
What are the anatomical differences in men and womans brains?
Women have:
- Slighlty smaller brains
- Thicker corpus callosum
- Share function hemispheres
- Slight difference in diencephalon/ telencephalon
What are the two categories of the role of sex hormones?
- Organisational effects
2. Activational effects
Outline organisational effects
- Prenatal: genetics -> sex organs -> hormones
• determines which system we follow - permanant, influence brain and sex organ development
Outline activational effects
- occur later in life, after development of sex organs
- e.g. puberty or menopause
What are the 3 types of sex organs
- Gonads
- 1st to develop - via genetics - Internal sex organs
- precursers for male and female internal organs are present in embryo, default = girl - external genitalia
- visibile sex organs, masculine development requires androgens