Lecture 8 - Substance Use & Disorders Flashcards
Which substances are most used in the general Canadian population?
Caffeine, tobacco, Alcohol, Cannabis, amphetamines, hallucinogens, problematic prescriptions.
How does the frequency of drinking change with age, income, and education?
It increases.
How does smoking and elicit drug use change with age, income, and education?
It decreases
How do the effects of drinking change with age?
Older adults are more susceptible to the effects of alcohol d/t increased body fat, reduction of lean mass, reduction of total water volume, and increases incidences of polypharmacy.
Which substance costs the most for Canada in the categories of healthcare, lost productivity, and criminal justice?
Alcohol, followed by the tobacco.
What is a substance use disorder?
A chronic and recurrent use of a substance over 12 months, which is compulsive and characterized by a continued use despite physical and psychological harms.
Diagnosis is specified according to substance.
+ 11 diagnostic criteria that determine severity of the illness.
What determines the severity of a substance use disorder?
Based on 11 diagnostic criteria:
Mild - 2-3 criteria
Moderate - 4-5 criteria
Severe - 6-7 criteria
Must be present within a a 12 month period
What are the 11 criteria to a substance use disorder?
- Substance often take in larger amounts or over a longer period of time than intended
- There is a persistent desire or unsuccessful effort to cut down or control substance use
- A great deal of time is spent in activities necessary to obtain, use, or recover from the effects of the substance
- Cravings
- Recurrent use resulting in failure to fulfill major role obligations at work, school, or home.
- Continues use despite having persistent or recurrent social or interpersonal problems caused by or exacerbated by the effects of the substance
- Important social, occupational or recreational activities are given up or reduced because of use
- Recurrent use situations in which it is physically dangerous
- Cont use despite knowledge or having persistent or recurrent physical or psychological problem that is likely to have been caused by or exacerbated by the substance.
- Tolerance
- Withdrawal
What is tolerance?
Either:
a - a need for markedly increased amounts of the substance to achieve intoxication or desired effect
or
b - marked by diminished effect with continued use of the same amount of a substance
What is withdrawal?
Manifests as either:
a - the characteristic of withdrawal syndrome
b - the same (or closely related) substance are taken to relieve or avoid withdrawal symptoms
What are the four Cs of substance use disorder?
Compulsive use
Cravings
Continued use despite serious consequences
Can’t stop.
What kinds of factors contribute to the etiology of substance disorders?
–> Environmental/cultural
–> Biology
–> Psychological
How does substance use change the reward system of the brain?
Dopamine reward system change physically to respond positively to drug use
–> More common with faster acting substances d/t direct cause and effect, such as IV, inhaled, or smoked drugs
How does the psychological cycle of tolerance and use develop?
Pleasure –> repeat use –> tolerance –> increased use
What personality phenotypes are associated with alcohol use disorder?
Neuroticism, impulsivity, extroversion.
What is the psychoanalytical perspective on substance use?
Substance use may be caused caused by conflicts amongst components of the self, fixation on infantile past, and/or seeking sensuous satisfaction
Failure of the ego to response issues between conscious and instincts (id) can lead to maladaptive coping responses
How does developmental theory explain substance use?
Substances are used to full an empty space left by a lack of healthy attachment during childhood.
Why does the use of crack cocaine precipitate the spread of hep c?
Burning of the lips through use of a pipe and spread blood between between users.
What is a concurrent disorder? What kind of disorders are usually associated with it?
Psychological/psychiatric disorder + substance use disorder
Often anxiety related, mood disorders, eating disorders.
What should you assess when assessing someone for use of substances?
- Name of substance
- Quantity used (or amount spent)
- Frequency (+ first daily dose w nic)
- Number years using
- Age of first use
- Route of administration
Explore reasons for substance use, past harms, past attempts to reduce consumption.
Ask about the clients goals about substance use.
If a person reports IV or inhaled drug use, what further assessments must be completed?
Ask:
Do you have access to sterile needles or inhaled supplies?
Do you or have you shared injection supplies with other people
What is the most important question to ask someone who is using substances?
Ask the client what their goal is.
Alcohol increases what psychiatric risks?
Alcohol can worsen effects of existing psychiatric conditions and may increase the risk of depression, suicide, homicide, and the risk of harm to self and others.
what makes alcohol with other substances so dangerous?
Causes respiratory CNS depression, disinhibition, and has cumulative effects when combines with barbiturates, benzos, psychotropic medications, and opioids.
How does chronic alcoholism kill people?
Cirrhosis, portal HTN –> esophageal varices –> hemorrhage, hepatic encephalopathy.
How does alcohol affect males and females differently?
Women metabolize alcohol differently than men and are more likely to experience adverse physiological effects.
Men become more impulsive and are more likely to cause harm to others.
What tools are available for assessing alcohol use?
Alcohol Use Disorder Identification Test (AUDIT)
–> Consists of 10 questions about recent use, dependence, and related problems
CAGE Questionnaire
C - effort to Cut down
A - Annoyed by criticism of drinking
G - Guilty
E - Eye-Opening: Drink in the morning to steady nerves or a hangover?
What is the threshold for alcohol intoxication?
At what rate does the body eliminate alcohol?
0.08% (80 mg/dL)
–> 5.5 hours for elimination because the body can eliminate approx 15 mg/h
What are the three levels are alcohol withdrawal?
Minor, Intermediate, Major (delirium tremens)
What does minor ethanol withdrawal look like? How long does it take to resolve?
Anxiety, N/V, coarse tremor, sweating, tachy, HTN, headache, insomnia
–> Usually resolves within 48-72 hours
What does intermediate ethanol withdrawal look like?
Minor symptoms plus seizure, dysthymias, and/or hallucinations
–> Pts retain insight into unreal nature or hallucination and remain oriented and alert.