Lecture 8- GIngival diseases 2 Flashcards

1
Q

oral involvement alone is common in …

A

lichen planus

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2
Q

… has characteristic skin lesions (wickham striae)

A

lichen planus

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3
Q

lichen planus can present as a …. at the gingival margin or as reticulated ….. lesions

A

patchy inflammation

hyperkeratotic

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4
Q

papular, reticular, plaque-like forms of lichen planus are usually …

A

asymptomatic

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5
Q

atrophic, ulcerative, bullous forms of lichen planus are usually ….

A

symptomatic

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6
Q

Do you need a biopsy to dx lichen planus?

A

yes

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7
Q

what do you see in histology of lichen planus

A

deposits of IgM, C3, C4, and C5

fibrin in the basement membrane

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8
Q

… is a group of disorders in which autoantibodies towards components of the BM result in detachment of the epithelium from the CT

A

pemphigoid

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9
Q

histology of pemphigoid is that there are autoantibody rxns against … and …. components

A

hemidesmosome

lamina lucida

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10
Q

pemphigoid has deposits of …

A

C3, IgG and other Ig’s

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11
Q

3 types of pemphigoid

A

bullous

benign mucous membrane

cicatricial (scar formation)

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12
Q

pemphigoid has female or male predominance?

A

female >50

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13
Q

the … sign is when the rubbing of gingiva creates a bull formation and is a sign of which disease?

A

nicholsky

pemphigoid

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14
Q

tx for pemphigoid?

A

plaque removal with daily use of chlorohexidine and/or topical corticosteroid

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15
Q

… involves a formation of intraepithelial bullae in skin and mucous membranes

A

pemphigus vulgaris

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16
Q

… has a strong genetic background (jewish and mediterranean)

A

pemphigus vulgaris

17
Q

histology of pemphigus vulgaris?

A

acantholysis (due to destruction of desmosomes)

18
Q

which disease will have a butterfly lesion on the nose?

A

lupus

19
Q

histology of lupus

A

increased width of BM