Lecture 12- Aggressive Periodontitis Flashcards
Common features of aggressive periodontitis
patient otherwise healthy
severe and rapid bone loss
familial aggregation
in aggressive periodontitis, patient shouldnt have any … condition
systemic
what age range is affected with LAP
puberty-20
in LAP, CAL MUST affect at least one
1st molar
in LAP, no more than 2 teeth are affected other than…
1st molars and incisors
in LAP, CAL is inconsistent with….
plaque and calculus
T/F in LAP, there is relatively more gingival inflammation
false
In LAP, there is robust serum antibody response of
IgG2
T/F LAP is self limiting
true
age range for GAP is usually under …. but can affect older patients too
30
at least ….. teeth other than 1st molars and incisors must be involved for GAP
3 permanent teeth
GAP has a pronounced …. nature of destruction
episodic
T/F GAP has relatively intense gingival inflammation
true
T/F GAP has a poor antibody response
true
which main bacteria is associated with LAP?
particularly …
Aa
JP2 clone, serotype b
Aa has … which kill PMNs and macrophages
leukotoxins
Aa has … which activates cells to produce PGs, IL-1b and TNF-a
LPS
Aa has … which degrades collagen fibers
collagenases
Aa has … and … suppressing factors
lymphocyte and chemotactic
Aa can … across the JE and invade the …
translocate
CT
in east asian population, which bacteria is most commonly assoc. with LAP
p. gingivalis
p. gingivalis has…. like … and …
proteinases
gingipains
collagenases
p. gingivalis has…. which activates cells to produce PGs, IL-1b and TNF-a
LPS
p. gingivalis inhibits …. which decreases chemotaxis of PMNs
IL-8
proposed inheritance mode for LAP?
autosomal dominant
If you suspect AP, what is the 1st treatment principle
refer to periodontist
for AP, after referral, what should be done?
full mouth SRP in adjunct with systemic antibiotics
what antibiotics are common for tx of AP
amoxicillin+ metronidazole
ciprofloxacin+ metronidazole
what steps are needed after full mouth SRP + antibiotics ?
possibly periodontal surgery
meticulous periodontal supportive therapy
