Lecture 7 - Virology part 1

Question 1

why cant virus replivat alone

Answer 1

doesnt have al the[rotein dneeded for preploication

Question 2

what does obligate intracelular parasite mean

Answer 2

goes indode cells

Question 3

Viron=

Answer 3

virus particle - nucleic acid and genome surrounded by a cpasid= protien

Question 4

geome

Answer 4

dna or rna not both

Question 5

Dna to dna

Answer 5

replication

Question 6

dna t mrna

Answer 6

transcription

Question 7

mrna to protein

Answer 7

tranlsation

Question 8

rna to dna

Answer 8

reverse ranscriptade

Question 9

how virsus can interupt mran to dna

Answer 9

ssrna looks like the mrna ribosome bnd to ssrna - make protein - pos sense

Question 10

used to classify viruses

Answer 10

baltimore claasification

Question 11

railed phage

Answer 11

ds dna

Question 12

flue

Answer 12

ssrna neg sense

Question 13

hiv

Answer 13

ssrna pos sense w/ rna intermediate

Question 14

in virsu dna or rna surroinded by protein coat

Answer 14

capsid

Question 15

envolpe may made out of

Answer 15

lipid bilayer from host membrance

Question 16

thre shapes of virus

Answer 16

icosahedral- ball
helical
complex- phage

Question 17

iscohedral

Answer 17

b sheet and a helices

fold and form symetry- to protect genoke ithin- form capsdi

Question 18

helical virus

Answer 18

virus rna surrounded by structual subunit= capisomeres

Question 19

HIv protein bind to

Answer 19

CD4 receptor

Question 20

reverse transcriptase used to

Answer 20

expres gene to genome

Question 21

bacteriophage evolved to

Answer 21

inject genokme inot cell

Question 22

how virus replicate

Answer 22

attach pentrate uncoate biosynthesis assembly release

Question 23

what happenes in attachment phase

Answer 23

cell specific recportot bind

Question 24

penetration

Answer 24

fusion of encovoelpe

Question 25

uncoating

Answer 25

releases nucleic acid

Question 26

biosynthesis

Answer 26

replication adn prosuction mrna - early porteins produces for replication viral nucleic acids
mrna produce late proteinf - structural for new virions

Question 27

assembly

Answer 27

nucleic acids and structural proteind from viron

Question 28

relaease lysis or budding

Answer 28

envolpe from cell membrance or nuclear membrane = viral encoded oroetiens

Question 29

bacreiophages much faster replicationq no intracelularcompartments

Answer 29

have lytuc or lysogenic cycle - when gene comporated to host genpme

Question 30

phage determines if lytic to klysogenic

Answer 30

if ideal condidiotns lytic

Question 31

Growth curve virus replication

Answer 31

early nucleic acid protein coats assembly and releae

Question 32

influenxe

Answer 32

8 segments each segement - gene- protein

3 make mrna polymerase 2 1 a

Question 33

when do mutaions occur

Answer 33

when rna polymerase outs in wronfnuclotide in humna proof reading abiities so les likely

Question 34

Antigenic shift

Answer 34

reassoirtmnet - virus replicate with another virus

because segmented genome can get new versions of virus that immune system cant recognise

Question 35

what is swine flu

Answer 35

when pig infected with an dchicken flu anf human flu an d then pig infected wiht that adb burd and human can now in fect human- cant be recognised - influenae every year

Question 36

oritein mutate

Answer 36

antgenic drift

Question 37

protein change

Answer 37

antigenic shift

Question 38

HIv recptor

Answer 38

gp120 bind to CD4 RECPETOR ON WHITE B,ID CELLDIFFUSION MEMBRAN IN RNA RELEASED VIRUS ENX=ZYMES MAKE COPY GENOKME INOT =DNA AND DNA INCOOPERATE INTO VIRUS