Lecture 4 - Proteins Flashcards
fibrillin
amyloid
cystic firbrosis
marfan syndrom
plaques associated alzehiemers
cant transport chloride ions
7 classes of amino acids
acidic aliphatic hydroxylic basic aromatic sufur containug amidic
Acidic
negatively charged r group
basic
pos charged r group
sulfur amidic and hydroxylic
polar uncarged r groups
aliphatic
non polar hydrophobic methyl group
Aromatic
benzene ring
threonine
2 chiral carbons
3 bonds in primary
psi c-n phi c-cand peptide n-co
amino acids favour
trans but proline favour trans
wheres folding of proteins
made in cyroplasm chaperones prevent folding bring to mitochondria as transported they fold
collogen triple helix
alpha
fibrous proteins
stopn at secondary
collagen dustruption
ehlers danlos syndrome- skin stretchy, hypermobile, bruise easily
globlin alpha
immuniglobin
beta