Lecture 4 - Proteins Flashcards

1
Q

fibrillin
amyloid
cystic firbrosis

A

marfan syndrom
plaques associated alzehiemers
cant transport chloride ions

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2
Q

7 classes of amino acids

A
acidic
aliphatic 
hydroxylic
basic
aromatic
sufur containug 
amidic
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3
Q

Acidic

A

negatively charged r group

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4
Q

basic

A

pos charged r group

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5
Q

sulfur amidic and hydroxylic

A

polar uncarged r groups

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6
Q

aliphatic

A

non polar hydrophobic methyl group

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7
Q

Aromatic

A

benzene ring

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8
Q

threonine

A

2 chiral carbons

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9
Q

3 bonds in primary

A

psi c-n phi c-cand peptide n-co

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10
Q

amino acids favour

A

trans but proline favour trans

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11
Q

wheres folding of proteins

A

made in cyroplasm chaperones prevent folding bring to mitochondria as transported they fold

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12
Q

collogen triple helix

A

alpha

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13
Q

fibrous proteins

A

stopn at secondary

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14
Q

collagen dustruption

A

ehlers danlos syndrome- skin stretchy, hypermobile, bruise easily

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15
Q

globlin alpha

immuniglobin

A

beta

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16
Q

cofactors and coenzymes

A

help stability

17
Q

coenzymes

A

from vitamins

18
Q

cooperative binding

A

chnage from high anf low affinity

19
Q

Protein kinase a

A

binding is production CAMP active and releases substrate