lecture 7- independent assortment, linkage, and gene mapping Flashcards
chi square test
- used to determine the P of observing a particular distribution under a specific hypothesis
parental type
have same alleles as gametes that formed from F1 (B L and b l)
recombinant type
have different combination of alleles from those in the gametes that formed in F1(B l and b L)
crossing over
- breakage and rejoining of homologous DNA double helices
- visible in metaphase i as chiasmata
- occurs only between non-sister chromatids at the same place
- observed between linked loci on the same chromosome
chiasma
events that happen when sister chromatids that are not together attach to the non-sister chromatids they are interacting with
cis
recessive alleles on the same homologue (AB/ ab)
trans
recessive alleles on different homologs (Ab/ aB)
linked genes (cis dihybrid with crossing over)
in dihybrid meiosis, 50% recombinants (R) indicates that genes are on different chromosomes or far apart on the same chromosome
linkage map
recombination frequency (RF)=
#of recombinant (CO) progeny x 100%/ total # progeny
RF = genetic distance
CO = crossing over