lecture 2- mitosis and meiosis Flashcards
gene
genomic sequence corresponding to a unit of inheritance
locus
location of a gene on the physical map
cytology
chromosomes are stained for identification using special stains. the result is G banding pattern characteristic to each chromosome
G1
cells prepare for replication
S
DNA replicates and new chromosomes are formed
G2
cells prepare for mitosis or divison
mitosis
- asexual cell division
- continuum of events
- divided into 4 cytological phases
prophase
- chromosomes condensed and replicated chromosomes become visible
- chromosomes attach to spindle via kinetochore
- nucleolus and nuclear membrane start to disappear
metaphase
chromosomes align on the equatorial plane
anaphase
sister chromatids separate and migrate to opposite poles
telophase
cell division starts and reformation of nucleus and nucleolus
meiosis
- sexual cell division
- not a cell cycle, it is a linear progression of events
- occurs in germ cells
prophase I
- chromosomes condense and replicated chromosomes become visible
- homologous chromosomes pair or synapse
- nucleolus and nuclear membrane start to disappear
spindle starts to form
metaphase I
- homologous chromosomes pair at mid-plane
- nucleolus and nuclear membrane disappeared
- spindle forms
anaphase I
homologous chromosomes separate
telophase I
- cell division
- nuclear membrane may appear
prophase II
not much change
metaphase II
- spindle forms
- chromosomes align at mid-plane
- no pairing of chromosomes
anaphase II
- centromeres divide
- sister chromatids separate
telophase II
- nuclear envelope forms
- cells start to divide
difference between anaphase I and anaphase II
- I.) homologous chromosomes separate ( no centromere separation )
- II.) centromeres separate (sister chromatids separate)