lecture 7/8 Flashcards

1
Q

A fibers

A

myelinated
sharp first pain
mech / therm stimulated

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2
Q

C fibers

A

unmyelinated
poorly localized
mech/ther/chemical

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3
Q

where do A delta and C fibres synapse

A

posterior horn

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4
Q

where is first site of pain modulation

A

posterior horn

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5
Q

nociceptor specific neurons receive input from ____ and ____ they are specific for ____

A

C
A
pain

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6
Q

wide dynamic range neurons receive input from __ and __ and ___

A

AB fibers, C and A

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7
Q

interneurons receive __ input and play a role in ___

A

diverse

pain modulation

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8
Q

WDR can fire __ in ___ fashion

A

AP

graded

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9
Q

WDR and dependent on __ singling

A

C

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10
Q

T/F WDR can wind up and lead to sensitization

A

true

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11
Q

the amplification system that responds to __ fibres

A

wind up

C

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12
Q

wind up is a __ in threshold and ___ in sensitivity

A

reduction

increase

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13
Q

wind up priority ___

A

saliency

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14
Q

anterolateral system compromises fibres of ____ and ___ from SC to ___ and ___

A

pain / temp

brainstem / thalamus

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15
Q

tract that compromises only the fibres projecting from SC to thalamus

A

spinothalamic

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16
Q

medial system

A

affective motivational component
ouch
suffering

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17
Q

lateral system

A

discriminative localized

pain in left toe

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18
Q

medial system area of brain

A

anterior cingulate cortex

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19
Q

lateral system area of brain

A

primary somatosensory

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20
Q

chronic pain

A

chronic: inflammatory pain
neuropathic
idiopathic

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21
Q

example chronic inflatmmory pain

A

arthritis

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22
Q

example chronic neuropathic pain

A

postherpetic neuralgia

23
Q

example idiopathic pain

A

fibromyalgia

24
Q

maladaptive mechanisms

A

peripheral

central

25
Q

peripheral maladaptive mechanisms

A

sensitazation over expression of receptors

26
Q

central maladaptive mechanisms

A

wind up, changes in neurotransmitter receprots

disinhibition

27
Q

central sensitization types

A

para
dys
hyper
allodynia

28
Q

parethisia / dysesthesias

A

increased spontaneous activity

29
Q

hyperalgesia

A

reduced threshold for pain

30
Q

allodynia

A

non noxious stimuli interpreted as painful

31
Q

neuropathic pain symptoms

A

burning shooting electrical

32
Q

nociceptive pain

A

squeeze throbbing aching

33
Q

__ and __ fibres influence gut mobility

A

sympathetic and parasymp.

34
Q

sensory information from the gut comes from what two sources

A
parsympatethic fibers (physiological - full)
sympathies fibers (pain)
35
Q

T/F referred pain can be from visceral nerve to somatic area

A

true

36
Q

T/F referred pain can be from somatic nerve to somatic area

A

T

37
Q

what innervates diaphragm

A

phrenic

38
Q

cortical areas of limbic system

A

cingulate gyrus
parahippcampal
uncut

39
Q

subcortical structures of limbic system

A

amygdala

hippocampus

40
Q

hippocampus respsonsibel for

A

memory
learning
viceral / endocrine function
emotional behaviour

41
Q

types of memory

A

declarative / explcit

non declarative / implicit

42
Q

types of declarative / explicit memory

A

episodic (events)

semantic (factors

43
Q

Decartlive / explicit memories what brain area

A

hippocampus

cortical

44
Q

types of non declarative implicit memories

A

skills
habits
emotioanl memory

45
Q

brain for non declarative implicit memory

A

basal ganglia
cerebllum
Amy
cortical areas

46
Q

Case of HM

A

bi lateral hippocampus lesion
loss of recent memory
intelligence not affected

47
Q

____ memory system for delclartive memory

A

medial temporal lobe

48
Q

basic papez circuit

A

cingulate cortex
hippocampus
mamm body
thalamaus

49
Q

Amygala

A

emotional memories
fear
reward motivation
what important

50
Q

Case of Sm

A

bilateral Amy lesion

absesne sense of fear

51
Q

emotional attention

A

reflective system (involuntary / automated)

52
Q

Dopamine associated with wanting or liking

A

wanting

53
Q

addiction activation of ___

A

dopamine neurons from VTA