lecture 7/8 Flashcards
A fibers
myelinated
sharp first pain
mech / therm stimulated
C fibers
unmyelinated
poorly localized
mech/ther/chemical
where do A delta and C fibres synapse
posterior horn
where is first site of pain modulation
posterior horn
nociceptor specific neurons receive input from ____ and ____ they are specific for ____
C
A
pain
wide dynamic range neurons receive input from __ and __ and ___
AB fibers, C and A
interneurons receive __ input and play a role in ___
diverse
pain modulation
WDR can fire __ in ___ fashion
AP
graded
WDR and dependent on __ singling
C
T/F WDR can wind up and lead to sensitization
true
the amplification system that responds to __ fibres
wind up
C
wind up is a __ in threshold and ___ in sensitivity
reduction
increase
wind up priority ___
saliency
anterolateral system compromises fibres of ____ and ___ from SC to ___ and ___
pain / temp
brainstem / thalamus
tract that compromises only the fibres projecting from SC to thalamus
spinothalamic
medial system
affective motivational component
ouch
suffering
lateral system
discriminative localized
pain in left toe
medial system area of brain
anterior cingulate cortex
lateral system area of brain
primary somatosensory
chronic pain
chronic: inflammatory pain
neuropathic
idiopathic
example chronic inflatmmory pain
arthritis