lecture 7

Question 1

mechanism of action of benzodiazepines:

Answer 1

binds at the interface of the GABA receptor and leads to a reduction in neuronal excitability by inhibiting nerve transmission resulting in a calming effect

Question 2

drug self administration:

Answer 2

experimental method used with animals to identify if a substance has positive reinforcing effects. animals press a lever a set number of times resulting in the administration of a drug. if administration of a drug is reinforcing, an animal will work for more administration

Question 3

benzos are in schedule:

Answer 3

4. low potential for abuse and low risk of dependence

Question 4

drug discrimination:

Answer 4

experimental method in which animals identify whether a drug produces physical or behavioral effects similar to those produced by another drug with known pharmacological properties

Question 5

benzos substitute for one another in:

Answer 5

drug discrimination research similarly in their subjective effects profile

Question 6

associated problems with prescribing benzos and opioids:

Answer 6

increased risk of fatal overdose, increased risk of suicide, poorer treatment effectiveness/commitment

Question 7

boxed warnings:

Answer 7

highest safety-related warning for medications regarding combining the drugs and risk of respiratory distress, coma, and death

Question 8

serious withdrawal symptoms onset:

Answer 8

as early as days to weeks some symptoms lasting months/years

Question 9

disorder for not being able to quit benzos or opioids:

Answer 9

sedative, hypnotic, and anxiolytic use disorder

Question 10

in 2020 FDS decided to ass additional boxed warnings including risks of:

Answer 10

addiction, severe and dangerous withdrawal symptoms

Question 11

duration of bentos is recommended for:

Answer 11

short term use

Question 12

why are people using benzos for other reason than medically?

Answer 12

relax or relieve tension, help with sleep, get high, help with emotions. many for life related stressors

Question 13

symptoms of long term effects of bentos:

Answer 13

low energy, difficulty focusing, memory loss, nervous, sleep disturbances, sensitivity to sights and sounds, digestive issues, muscle weakness, body aches and pains

Question 14

reasons for benzodiazepines prescription:

Answer 14

situation anxiety/anxiety, insomnia, digestive, stomach/gut issues, restlessness (95%), muscle spasm, pain, nerve spasms

Question 15

treatment for benzodiazepines addiction:

Answer 15

motivational interviewing, coping skills, stress management, support groups, CBT