Lecture 6 - Metazoa Flashcards
Three types of metazoa/heminths?
- nematodes
- trematodes
- cestodes
What are nematodes?
round worms with complete digestive systems (mouth, intestine and anus)
two types of nematodes where the eggs are the infective stage?
- Enterobius vermicularis (pinworms)
2. Ascaris lumbricoides
Enterobius vermicularis
“pinworm”
- transmitted by ingestion of eggs in dust or direct contact
- type of nematode (round worm)
- humans are biological vectors of E.vermicularis because it spends its entire life cycle (including reproduction) in the human body
- live in the large intestine –> females migrate to anus and lay eggs on the skin around the anus
- is not serious but is super infectious
Ascaris lumbricoides
- type of nematode (round worm)
- lives in small intestine of pigs, cows, and horses
- has eggs in soil and the eggs have a hardy protein coat
- transmitted fecal-orally
- can be very large (up to 30cm)
- dioecious (have distinct sexes)
- humans are infected by the egg
- the eggs hatch in the intestines and then the larvae move to the lungs and trachae –> they come up the nose and mouth of kids but not adults due to the swallow reflex
four types of nematodes where the larvae is the infective stage?
- Hookworms
- Anisakis
- Trichinella spiralis
- Blood nematodes (Filaria) –> lymphatic filariasis and onchoceriasis
Hookworms
- type of nematode
- infects humans at the larvae stage
- transmitted by entering intact skin of bare feet (direct skin contact)
- enters the lymph nodes through the feet and then the circulatory system, it gets into the lungs and can be coughed up and then swallowed down into the intestine where they attach onto the intestinal walls with the hooks on their scolex (heads)
- they cause anemia because they suck blood
- eggs are excreted in human feces
Anisakis
- type of ‘fish nematode’
- infects humans at the larvae stage
- occurs when fish are not cleaned after they are caught, the eggs of Anisakis live in the intestines of the fish, and then they hatch and move into the flesh which gets eaten by humans
- the worm can borrow into the intestinal lining and lead to ulcers
Best ways to prevent Anisakis?
- heat fish up to 60 degrees celsius for 10 minutes
- blast freeze to -35 degrees celsius for 15 hours OR freeze at -23 degrees for 3 days
- clean fish (evisceration) and remove its guts as soon as possible
Trichinella spiralis
- type of nematode
- infects humans at larvae stage
- occurs when undercooked pork, boar, bear or walrus is ingested by humans
- causes muscle weakness
- this is because the larvae live in striated muscles including the heart and form “nurse cells” [encysts itself]
- particularly dangerous if it lives in the striated muscle of the heart because it causes mm. weakness
- difficult to treat
Two types of Filaria (blood nematodes) and examples?
- lymphatic filariasis –> adult worms live in the lymph tissue (i.e. elphantiasis)
- onchoceriasis –> adult worms live in subcutaneous tissue (i.e. river blindness)
what are microfilariae? How are they transmitted?
offspring of adult worm (larvae of filariae) that circulate through the blood stream or migrate through subcutaneous tissue
- they are transmitted by mosquitos and are common in africa, asia and latin america (in the tropics)
What is an example of a Trematode?
Schistomas
Schistoma
- trematode
- infects humans at larvae stage called cercariae
- contracted in fresh water ponds
- penetrates intact skin of humans
- adult schistomas have a coat of protein that they get from their host that hides them from the host’s immune system
- worms live in the venous plexus (veins above and around) the bladder or intestine
- eggs of schistomes cause inflammation
Three types of Schistoma infections in humans?
- S.haematobium
- S.japonicum
- S.mansoni