Lecture 6: Intro to Immunology Flashcards

1
Q

This is the resistance to infectious disease

A

Immunity

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2
Q

This is a collection of cells, tissues, and molecules that mediate resistance to infections

A

Immune system

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3
Q

This is a coordinated reaction of the immune system to infectious microbes

A

Immune response

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4
Q

This is the study of the immune system

A

Immunology

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5
Q

What is the principal function of the immune system?

A

Defense against microbial infections

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6
Q

Can the immune response be a barrier to transplantation and gene therapy

A

Yes

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7
Q

B and T lymphocytes are in what system?

A

Adaptive immunity

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8
Q

In the first few hours of infection, what events occur? What about several hours/days later?

A

a. The innate immune system responds rapidly to viral infection
b. Then the adaptive system responds after being activated by the innate

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9
Q

Is the innate immune system antigen-specific?

A

No, recognizes PAMPs and DAMPs instead

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10
Q

What immune system is “nonreactive to self”?

A

a. Innate
b. adaptive

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11
Q

Do you have memory in innate immunity?

A

no

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12
Q

What immune system is highly antigen-specific?

A

Adaptive immune system

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12
Q

What cell type is required for all humoral immune responses?

A

B lymphocytes

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13
Q

What cell type is required for all cell-mediated immune responses?

A

T cells

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13
Q

Cytotoxic and Helper T cells are the mediators of what immunity?

A

Cell-mediated immunity

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13
Q

antibodies/B-cells are the mediators of what immunity?

A

Humoral immunity

14
Q

What are the 2 major functional classes of effector T lymphocytes?

A

Helper T cells
Cytotoxic T lymphocytes

14
Q

The responsibility of these cells is specific recognition of antigens

A

Lymphocytes (B and T)

14
Q

This is when you ensure that distinct antigens elicit specific responses in adaptive immunity

A

Specificity

15
Q

This is when the immune system is able to respond to a large variety of antigens

16
Q

This is when responses are optimally generated for defense against different types of microbes

A

Specialization

17
Q

In addition to T cells, which cell types are required for initiation to all T cell-mediated immune
responses?

A

antigen-presenting cells

18
Q

Bone marrow produces what?

A

B lymphocyte

19
Q

Thymus produces what?

A

T lymphocyte

20
What are the stages of B and T lymphocytes?
a. Antigen recognition b. Proliferation c. Differentiation
21
T cell zone is found where?
Parafollicular cortex
22
B cell zone is found where?
Lymphoid follicle
23
After lymphocytes are activated by an antigen, B and T cells migrate
Towards each other and meet at the edge of the follicle
24
Does active immunity give you specification and memory?
a. Yes or both
25
If you get a microbial antigen (vaccine or an infection), what type of immunity will you get?
Active humoral immunity
26
When you administer serum (antibodies) from an immune individual to an uninfected individual, that is what type of immunity?
Passive humoral immunity
26
Does passive immunity give you specification and memory?
Only specification, no memory