Lecture 6: Intro to Immunology

Question 1

This is the resistance to infectious disease

Answer 1

Immunity

Question 2

This is a collection of cells, tissues, and molecules that mediate resistance to infections

Answer 2

Immune system

Question 3

This is a coordinated reaction of the immune system to infectious microbes

Answer 3

Immune response

Question 4

This is the study of the immune system

Answer 4

Immunology

Question 5

What is the principal function of the immune system?

Answer 5

Defense against microbial infections

Question 6

Can the immune response be a barrier to transplantation and gene therapy

Answer 6

Yes

Question 7

B and T lymphocytes are in what system?

Answer 7

Adaptive immunity

Question 8

In the first few hours of infection, what events occur? What about several hours/days later?

Answer 8

a. The innate immune system responds rapidly to viral infection
b. Then the adaptive system responds after being activated by the innate

Question 9

Is the innate immune system antigen-specific?

Answer 9

No, recognizes PAMPs and DAMPs instead

Question 10

What immune system is “nonreactive to self”?

Answer 10

a. Innate
b. adaptive

Question 11

Do you have memory in innate immunity?

Answer 11

no

Question 12

What immune system is highly antigen-specific?

Answer 12

Adaptive immune system

Question 12

What cell type is required for all humoral immune responses?

Answer 12

B lymphocytes

Question 13

What cell type is required for all cell-mediated immune responses?

Answer 13

T cells

Question 13

Cytotoxic and Helper T cells are the mediators of what immunity?

Answer 13

Cell-mediated immunity

Question 13

antibodies/B-cells are the mediators of what immunity?

Answer 13

Humoral immunity

Question 14

What are the 2 major functional classes of effector T lymphocytes?

Answer 14

Helper T cells
Cytotoxic T lymphocytes

Question 14

The responsibility of these cells is specific recognition of antigens

Answer 14

Lymphocytes (B and T)

Question 14

This is when you ensure that distinct antigens elicit specific responses in adaptive immunity

Answer 14

Specificity

Question 15

This is when the immune system is able to respond to a large variety of antigens

Answer 15

Diversity

Question 16

This is when responses are optimally generated for defense against different types of microbes

Answer 16

Specialization

Question 17

In addition to T cells, which cell types are required for initiation to all T cell-mediated immune
responses?

Answer 17

antigen-presenting cells

Question 18

Bone marrow produces what?

Answer 18

B lymphocyte

Question 19

Thymus produces what?

Answer 19

T lymphocyte

Question 20

What are the stages of B and T lymphocytes?

Answer 20

a. Antigen recognition
b. Proliferation
c. Differentiation

Question 21

T cell zone is found where?

Answer 21

Parafollicular cortex

Question 22

B cell zone is found where?

Answer 22

Lymphoid follicle

Question 23

After lymphocytes are activated by an antigen, B and T cells migrate

Answer 23

Towards each other and meet at the edge of the follicle

Question 24

Does active immunity give you specification and memory?

Answer 24

a. Yes or both

Question 25

If you get a microbial antigen (vaccine or an infection), what type of immunity will you get?

Answer 25

Active humoral immunity

Question 26

When you administer serum (antibodies) from an immune individual to an uninfected individual,
that is what type of immunity?

Answer 26

Passive humoral immunity

Question 26

Does passive immunity give you specification and memory?

Answer 26

Only specification, no memory