Lecture 6- hemostasis Flashcards by April Stalevicz | Brainscape

Q

Hirudin, bivalrudin, and argatroban are all

A

direct thrombin inhibitors

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Q

3 drugs that block platelet aggregation

A

aspirin

clopidogrel (plavix) and ticlopidine

epifibatide and tirofiban

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Q

Aspirin mechanism ….

A

inhibition of Thromboxane A2 synthesis

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Q

Clopidogrel and ticlopidine mechanism?

A

blockage of ADP receptors

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Q

Epifibatide and Tirofiban mechanism?

A

blockage of GPIIb/IIIa

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Q

Antidote for warfarin overdose?

A

Vitamin K, Aqua Mephyton

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Q

Antidote for heparin overdose?

A

Protamine

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Q

Heparin and fondaparinux are …

A

indirect thrombin inhibitors (act on AT)

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Q

Heparin binds to AT and increases its activity by

A

1000 fold

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