Lecture 6: Choroid Flashcards

1
Q

the choroid is what layer of the eye?

A

The vascular layer of the eye (tunica vasculosa)

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2
Q

what color is the choroid and why?

A

Dark brownish color due to melanocytes

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3
Q

what is the choroid composed of?

A

blood vessels, melanocytes, and connective tissues

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4
Q

the choroid is firmly attached to what 3 locations?

A
  • Scleral spur
  • Exit of vortex veins
  • Optic nerve
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5
Q

The Vascular layer is composed of three structures; what are they?

A
  • iris (anteriorly)
  • ciliary body
  • choroid (posteriorly)
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6
Q

what three structures form a continuous tract?

A
  • iris (anteriorly)
  • ciliary body
  • choroid (posteriorly)
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7
Q

the choroid is the posterior aspect of what?

A
  • posterior aspect of the uveal tract
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8
Q

what does the choroid contain?

A

Contains blood vessels, melanocytes, connective tissue, & mucinous extracellular fluid

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9
Q

what is the primary function of the choroid?

A

Nourishes outer layers of the retina

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10
Q

what is the secondary function of the choroid?

A

Serves as a heat exchange

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11
Q

what structure accounts for 85% of the blood flowing through the eye?

A

choroid

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12
Q

list the choroid layers from inner to outer.

A
  • Bruch’s membrane
  • Choriocapillaris
    (Capillary layer)
  • Choroidal Stroma
    (Vessel layer)
  • Suprachoroid lamina
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13
Q

where is the choroid located?

A

Located between sclera and retina

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14
Q

where does the choroid extend?

A

Extending from ora Serrata to optic nerve

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15
Q

where is the thickest and thinnest part of the choroid?

A

Thickest 0.2mm at the posterior pole

Thinnest 0.1mm at ora Serrata

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16
Q

Suprachoroid lamina has a potential space between what?

A

Potential space between the sclera and choroidal vessels

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17
Q

what does the Suprachoroid lamina contain?

A

Contains collagen bands, fibroblast and melanocytes

18
Q

what causes the Suprachoroid lamina to detach?

A

Can swell without causing detachment

19
Q

what does the Suprachoroid lamina carry?

A

Carry LPCA and LPCN from posterior to anterior

20
Q

Choroidal stroma

A

Pigmented vascularized, loose CT layer

21
Q

what does the Choroidal stroma contain?

A

containing melanocytes,

fibroblasts, macrophages, lymphocytes, and mast cells

22
Q

(Choroidal stroma) Haller’s layer:

A

outer with large lumina vessels

23
Q

(Choroidal stroma) Sattler’s layer:

A

medium-sized vessels

24
Q

what do the venules in the Choroidal stroma join to become?

A

The venules join to become four large vortex veins

25
Clinical relevance: Choroidal stroma
Clinical relevance: high density of melanin granules àpotential for choroidal melanoma (can not miss in the clinic!!!)
26
Choriocapillaris:
Specialized capillary bed, a single layer of anastomosed, fenestrated capillaries with wide lumina
27
where are Choriocapillaris densest?
macula
28
what is a unique structure to the choroid and what does it provide?
pericytes (provide local blood flow regulation)
29
Bruch’s membrane: what layer of the choroid is it?
The innermost layer of the choroid fuses with the retina Allow nutrients inflow to the retina and remove waste products
30
what are the five layers of Bruch’s membrane?
1. BM of RPE 2. Inner collagenous zone 3. Elastic layer 4. Outer collagenous zone 5. BM of Choriocapillaris
31
T/F: Bruch’s membrane acellular
T
32
what does Bruch’s membrane contain elements of
elements of the choroid and RPE
33
what does Bruch’s membrane surround?
it surrounds the optic disc and extends peripherally to the ora serrata
34
where is Bruch’s membrane the thickest and the thinnest
* Thickest near the optic disc (2-4 microns) | * Thinner peripherally (1-2 microns)
35
what is the posterior choroid supplied by?
10- 20 SHORT POSTERIOR CILIARY ARTERIES (SPCA)
36
what is the anterior choroid supplied by?
2 LONG POSTERIOR CILIARY ARTERIES (LPCA) and Anterior Ciliary arteries (ACA)
37
where does the anterior and posterior systems meet?
The two systems meet at the equator and are connected with each other via recurrent vessels
38
Drusen:
deposit of waste material from the retina characteristics of AMD
39
where is Drusen found?
Between the inner collagenous layer of Bruch’s and BM of RPE
40
Angoid streaks:
damage to the elastic layer of bruch's **Psuedoxanthoma elasticum, ehlersdanlos syndrome, pagets disease, sickle cell disease, and Idiopathic (PEPSI)
41
Choroidal neovascular membranes (CNVM) results from what?
a break in bruch's membrane
42
what casues Choroidal neovascular membranes (CNVM)?
Due to pathological myopia, Exudative ARMD, Histoplasmosis, Choroidal rupture