Lecture 6: Chemistry of medicines to treat GIT inflammation

Question 1

What drugs are used to treat GIT inflammation?

Answer 1

• Sulfasalazine
• Mesalazine
• Balsalazine
• Olsalazine

Question 1

What is the mechanism of action of sulfalazine?

Answer 1

Sulfalazine is a pro drug. It is broken down to the active metabolite 5 aminosalisillic acid - mesalazine. Its site of action is the colon.