Lecture 4: Management of Gastro-Intestinal and Endocrine Disease Flashcards
1
Q
Name alginates
A
Peptac
Gaviscon
2
Q
Name antacids
A
Co-magaldrox
Magnaesium triscilicate
3
Q
What are the indications for PPI?
A
Ulcer disease
H pylori eradication
Dyspepsia
GORD
Prevention of NSAID damage and re bleed after surgery
4
Q
What are the cautions for PPIs?
A
- Increased risk of bone fracture
- Increased risk of C diff infection
- Mask symptoms of cancer
- Rebound hyper secretion of acid on cessation
5
Q
What are the PPI drug interactions?
A
- esomeprazole and omeprazole decrease antiplatlet effect of clopidogrel
- pantoprazole may increase the anticoagulant effect of warfarin (coumarins)
6
Q
What are the side effects of PPI?
A
- Abdominal pain
- Headache
- Arthralgia
- Parasthesia
- confusion
- Gynaecomastia
7
Q
What are the side effects of H2 receptor antagonists?
A
- diarrhoea
- dizziness
- erythema multiform
- hepatitis
- confusion
8
Q
What are the drug interactions of H2 receptor antagonists?
A
- cimetidine increases blood concentration of erythromycin
- famotidine and ranitidine reduce plasma concentration of atazanavir
8
Q
What are the drug interactions of H2 receptor antagonists?
A
- cimetidine increases blood concentration of erythromycin
- famotidine and ranitidine reduce plasma concentration of atazanavir
