Lecture 6- Cancer metabolism Flashcards
1
Q
What is the Warbug effect?
A
-The Warburg Effect is defined as an increase in the rate of glucose uptake and preferential production of lactate, even in the presence of oxygen
Slide 3-5
2
Q
What pathways contribute to the increased glycolysis?
A
Slide 6
3
Q
What is paraganglioma and how may its metabolism be deregulated in the familial version?
A
Slide 9-10
4
Q
How may deregulated metabolism predispose you to renal carcinoma?
A
Slide 11-12
5
Q
How is deregulated metabolism associated with VHL disease?
A
Slide 14-15
6
Q
What is glutamine and how may it be implicated in cancer?
A
Slide 16-20
7
Q
How may mutated IDH1 and IDH2 contribute to cancers?
A
Slide 22-30
8
Q
A
