Lecture 4- Cellular responses to oncogene activation Flashcards

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1
Q

Discuss how MYC can cause cancer.

A

Slide 3-6

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2
Q

Discuss how HRAS can cause cancer

A

Slide 7-10

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3
Q

Describe a model for proto-oncogene-induced proliferation

A

Slide 11

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4
Q

Discuss the activation of p53 by oncogenes and its regulation

A

Slide 12-17

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5
Q

How does E2F correlate with oncogene activation?

A

Slide 18

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6
Q

How does triple KO of all three pocket proteins affects cell?

A

Slideb 19-23

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7
Q

Discuss survival signalling in cancer development.

A

Slide 24-31

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8
Q

Discuss NOTCH as a potential proto-oncogene or tumour suppressor.

A

Slide 32-37

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