Lecture 4- Cellular responses to oncogene activation Flashcards
1
Q
Discuss how MYC can cause cancer.
A
Slide 3-6
2
Q
Discuss how HRAS can cause cancer
A
Slide 7-10
3
Q
Describe a model for proto-oncogene-induced proliferation
A
Slide 11
4
Q
Discuss the activation of p53 by oncogenes and its regulation
A
Slide 12-17
5
Q
How does E2F correlate with oncogene activation?
A
Slide 18
6
Q
How does triple KO of all three pocket proteins affects cell?
A
Slideb 19-23
7
Q
Discuss survival signalling in cancer development.
A
Slide 24-31
8
Q
Discuss NOTCH as a potential proto-oncogene or tumour suppressor.
A
Slide 32-37