Lecture 1- Beyond the 'Hallmarks'

Question 1

What is cancer? What are its hallmarks?

Answer 1

Slide 3-4

Question 2

Discuss tumorigenesis as aberrant differentiation.

Answer 2

Slide 6-7, 14-17

Question 3

Discuss the heterogeneity of cancer cells.

Answer 3

Slide 8

Question 4

Discuss cancer stem cells.

Answer 4

Slide 9-13

Question 5

Ho can the expression profiles of tumours be studied?

Answer 5

Slide 19-27

Question 6

How can B cell differentiation lead to different types of lymphoma?

Answer 6

Slide 28-29

Question 7

How do B cell lymphomas interact with CD8+ T cells?

Answer 7

Slide 31-50

Question 8

What are some applications of next-generation sequencing?

Answer 8

Slide 34

Question 9

What did the pan-cancer analysis of whole genomes reveal?

Answer 9

Slide 35-44

Question 10

How can we experimentally recapitulate colorectal cancer?

Answer 10

Slide 46