Lecture 6 Flashcards
Motor end plates have many ____
mitochondria
Synaptic vesicles with acetylcholine do what?
Release neurotransmitters via exocytosis
Where are the dense bars located?
anchored to the presynaptic membrane
Where is the synaptic gutter and what does it do?
This is a groove or furrow in the surface of a sarcolemma in which the axon terminal makes contact with the sarcolemma.
What are subneural clefts and where are they located?
Are smaller clefts or troughs in the bottom of the synaptic trough.
What is the synaptic cleft and where is it located?
This is a very narrow but real gap between the axolemma of the axon terminal and sarcolemma of the innervated muscle fiber.
In the Sarcolemma of skeletal muscle tubular channels remain __ until___ attach to ____
closed; two acetylcholine molecules; its alpha subunits
What does depolarization depend on?
it depends on ACH released.
The sarcolemma of the skeletal muscle has what type of channels?
acetylcholine gated ion channels
State the number of acetylcholine molecules that attach to each ligand gated channels
2
Ach is synthesized in __ of the nerve axon terminal
cytosol
What are calcium ions thought to do during a transmission of an action potential?
Calcium ions are thought to draw synaptic vesicles closer to neurolemma next to the voltage gated calcium channels
Define end plate potential
It initiates an action potential on the sarcolemma after large numbers of sodium ions pass through the muscle fiber membrane
State the number of acetylcholine molecules that attach to each ligand gated channels
2
Identify the subunits to which acetylcholine attaches
Alpha
