Lecture 6

Question 1

Why do we need to use statistical tests for our experimental data?

Answer 1

to determine whether results are significant or just by chance

Question 2

Define p-value.

Answer 2

The probability that results of another experiment will deviate from expected results by chance

Question 3

Define autosomal inheritance.

Answer 3

pattern of inheritance when gene is located on a NON-sex chromosome

Question 4

Define pedigrees.

Answer 4

A diagram that shows the relationships between family members and inheritance of traits through generation
iow. a gene family tree

Question 5

Define carrier.

Answer 5

a person who has or “carries” a genetic difference but doesn’t have the disease

Question 6

Define proband.

Answer 6

the first person in a family identified to have a condition or disorder

Question 7

autosomal dominant

Answer 7

trait occurs in both heterozygous and “dominant” homozygous genotype

Question 8

recessive inheritance

Answer 8

only appears if homozygous for the recessive allele

Question 9

Chi-Square Test

Answer 9

statistical test used to determine if there is a significant difference between observed phenotypes and predicated ratios
x<0.5 is null hypothesis is rejected

Question 10

nucleosomes=

Answer 10

Total base pairs/(146bp of core DNA length +linker DNA length)