LECTURE 6 Flashcards

Emergency COntraceptive and Medical Abortion

1
Q

What are the different types of EC ?

A

Hormonal : Levonorgestrel , Ulipristal and uzpe method

Intrauterine COntraceptive : Copper or LNG IUD

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2
Q

What are the main mechanisms by which hormonal EC acts ?

A

*** interferes with ovulation through Progestin

Prevent fertilization ( stops sperm binding)

prevent contractility to more the ovum through the fallopian tube

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3
Q

Which EC prevent ovulation ?

A

LNG EC
Uliprsital
Cu-IUD

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4
Q

Which EC prevets fertilization ?

A

Cu-UID

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5
Q

Which EC prevents implantation ?

A

Cu-IUD

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6
Q

When does LNG EC works the best ?

A

before the LH surge and prevent ovulation

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7
Q

What is the timeframe of effectiveness of LNG EC ?

A

3 days andmaybe 5 days

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8
Q

What is the most important DDI to remenber for its interaction with EC ?

A

Rifampin: inducer that cause the increase in the metabolism of EC

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9
Q

Whar are the ADR of hormonal EC ?

A

Spotting/breakthrough, abdominal cramping, nausea/vomiting and others

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10
Q

After the use of LNG, when can we expect the return of menses ?

A

~ 3 weeks

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11
Q

What is the MOA of ulipristat ?

A

selective progesterone agonist or antagonist
directly affects the follicular rupture

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12
Q

Ulipristatc an act up until ?

A

5 days

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13
Q

How many days should the patient wait after taking Plan B forfor starting CHC/POP ?

A

Wait 5 days

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14
Q

How do I do the yupze regimen ?

A

100 mg extradio, 500 mg LNG or 1 mg Norgetrol
repeat after 12hours

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15
Q

If pt want to use CHC after ulipristat , what can you let them know ?

A

hold CHC/POP for 5 days but have have 14 days backup

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16
Q

What is gestational age ?

A

The time after the last period day

17
Q

What is the MOA of Mifepristone ?

A

Progesterone antagonist on the endo/myometrium
+ anti glucocorticoids effect

leads to uterine contraction, cervical softening and dilation

18
Q

What is the MOA of Misoprostol ?

A

Synthetic PGs
Uterine contraction , soft cervix to expel pregnancy

19
Q

How effective is MIFE/MISO ?

A

95-98% gestational up to 70 days

20
Q

How soon can you ovulate after MIFE/MISO ?

A

early as 8 days afterwards